In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
[Strategies and Barriers to the Implementation of Continuing Education in Sentinel Hospitals for the Surveillance of COVID-19 Vaccine Safety in Honduras, 2022-2023Formação continuada: estratégias e barreiras de implementação em hospitais sentinela para a vigilância da segurança das vacinas contra a COVID-19 em Honduras, 2022-2023]. [PDF]
Zúniga C +11 more
europepmc +1 more source
Psychiatric co-morbidity in primary care and hospital referrals, Saudi Arabia
N.A. Qureshi +4 more
openalex +1 more source
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
[Alzheimer's and Its Diagnosis: Are We Prepared to Accompany Our Patients? Shared Care Planning as a Relational Framework]. [PDF]
Eimil-Ortiz M +2 more
europepmc +1 more source
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
[Pathological anatomy and its importance in the hospital setting]. [PDF]
Dragustinovis-Valdez IY +1 more
europepmc +1 more source
Plasma folate studies in HIV-positive patients at the Lagos university teaching hospital, Nigeria
Osunkalu Vincent +6 more
openalex +2 more sources
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source

