Results 111 to 120 of about 1,279,602 (365)

Canal Wall Down Timpanoplasty with Partial Mastoid Obliteration in Children and Adults Affected by Chronic Otitis Media with Cholesteatoma

open access: yesJournal of International Advanced Otology
Background: The aim of the study is to evaluate the incidence of recurrence of acquired cholesteatoma and functional outcomes in patients who underwent CWD tympanoplasty with cavity obliteration using an inferior-based musculoperiosteal flap.
Mariapaola Guidi   +6 more
doaj   +1 more source

Trajectories of risk after hospitalization for heart failure, acute myocardial infarction, or pneumonia: retrospective cohort study

open access: yesBritish medical journal, 2015
Objective To characterize the absolute risks for older patients of readmission to hospital and death in the year after hospitalization for heart failure, acute myocardial infarction, or pneumonia. Design Retrospective cohort study. Setting 4767 hospitals
K. Dharmarajan   +10 more
semanticscholar   +1 more source

Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

open access: yesAdvanced Science, EarlyView.
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang   +9 more
wiley   +1 more source

Mouse oocyte development - Methods and Protocols

open access: yesEuropean Journal of Histochemistry, 2018
The Springer Protocols series “Methods in Molecular Biology” has published its 1818th volume which is entirely devoted to the development of the female gamete: the oocyte.
Manuela Monti
doaj   +1 more source

Irisin Attenuates Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension via Ubiquitin‐Mediated Regulation of ENO1

open access: yesAdvanced Science, EarlyView.
Irisin is a crucial plasma biomarker and promising therapeutic target that reflects disease severity, pulmonary vascular remodeling status and clinical outcome in patients with pulmonary arterial hypertension (PAH). As a novel protective factor, irisin is downregulated in PAH. By ubiquitination, irisin promotes Enolase 1 degradation and suppresses cell
Na Sun   +15 more
wiley   +1 more source

Biomarkers and clinical scores to identify patient populations at risk of delayed antibiotic administration or intensive care admission

open access: yesCritical Care, 2019
Background The performance of blood biomarkers (mid-regional proadrenomedullin (MR-proADM), procalcitonin (PCT), C-reactive protein (CRP), and lactate) and clinical scores (Sequential Organ Failure Assessment (SOFA), National Early Warning Score (NEWS ...
Juan Gonzalez del Castillo   +13 more
doaj   +1 more source

THE IMPORTANCE OF PLAY DURING HOSPITALIZATION OF CHILDREN

open access: yesMateria socio-medica, 2015
Introduction: Play constitutes an essential parameter of the normal psychosomatic development of children, as well as their statutory right. It is also an important means of communication in childhood.
K. Koukourikos   +3 more
semanticscholar   +1 more source

Lactate‐Activated GPR132‐Src Signal Induces Macrophage Senescence and Aggravates Atherosclerosis Under Diabetes

open access: yesAdvanced Science, EarlyView.
Elevated lactate in diabetes activates the GPR132‐Src pathway in macrophages, inducing macrophage senescence and further enhancing foam cell formation. This mechanism exacerbates atherosclerotic progression. Abstract Diabetes is widely acknowledged as a significant risk factor for atherosclerosis, facilitating plaque formation through various ...
Xiaofeng Ge   +10 more
wiley   +1 more source

Hospitalization Type and Subsequent Severe Sepsis.

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2015
RATIONALE Hospitalization is associated with microbiome perturbation (dysbiosis), and this perturbation is more severe in patients treated with antimicrobials.
H. Prescott   +4 more
semanticscholar   +1 more source

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