Results 111 to 120 of about 902,907 (292)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka +7 more
wiley +1 more source
TRANSIÇÃO DE SAÚDE-DOENÇA DO SER ADOLESCENTE HOSPITALIZADO
Cogitare Enfermagem, 2005 Reflexão teórica a respeito do processo de transição a que passa o adolescente ao vivenciar a simultaneidade da adolescência, adoecimento e hospitalização.
Tânia Maas +1 more
doaj +1 more source
Burden of Influenza in Patients Visiting Emergency Department for Treatment of Influenza Like Illness at THQ Hospital Shujabad, Pakistan [PDF]
, 2020 Background: Viral infection of the respiratory tract is a common illness syndrome in humans. Human respiratory tract is infected by large number of viruses. Self-constraining infections are caused by most of them e.g.
Chaudhry, M. (Mamoona) +4 more
core
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Clinics and PracticeBackground: Psychological distress is a predictor of future health and disease data, with consequent implications for both the patient and the healthcare system.
Ana María Gómez García +1 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
, 2020 1. 本研究では，東京都，大阪府，神奈川県の3自治体を取り上げ，簡単な感染症数理モデルをあてはめて種々のデータと整合性のある形で新型コロナウイルス感染症の感染実態を説明することを試みた．項目4から8がモデルによる解析の主たる結果である．2. 解析に用いるモデルはSIRモデルの単純な一変種で，未感染者・感染者・免疫保持者の割合の時間的変化を記述する．感染者は感染後一定期間(15日間) は他人に感染させる力があり，その後免疫保持者となる．感染者が感染力を持つ期間の感染力は(感染力パラメータβ ...
土谷 隆 +1 more
core +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source