Results 201 to 210 of about 445,978 (269)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Early Risk Stratification for Subsequent Small Airway Dysfunction in Hospitalized Children with <i>Mycoplasma Pneumoniae</i> Pneumonia: A Retrospective Cohort Study. [PDF]

Children (Basel)
Ma R, Song J, Fu Y, Li R, Feng T, Yu Z, Zhang M, Jin S, Zhang X.   +8 more
europepmc   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

The impact of pediatric influenza and COVID-19 hospitalization on parental attitudes toward vaccination. [PDF]

Hum Vaccin Immunother
Rzymski P, Szczepańska B, Wasielewska Z, Pawłowska M, Cywińska K, Świerczynski J, Dobrzeniecka A, Małecka I, Poniedziałek B, Flisiak R, Zarębska-Michaluk D.   +10 more
europepmc   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Assessment of Functioning and Disability Based on WHODAS 2.0 and Related Factors Among People Aged 80 and Over Hospitalized in a Geriatric Ward in Southeastern Poland. [PDF]

Med Sci Monit
Brożonowicz J, Sozańska A, Sozański B, Wilmowska-Pietruszyńska A, Orzech-Janusz E, Wiśniowska-Szurlej A.   +5 more
europepmc   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Prevalence and outcomes of bacterial co-detections by blood culture among children and adults hospitalized with laboratory-confirmed influenza, Influenza Hospitalization Surveillance Network, 2022-2024. [PDF]

Clin Infect Dis
Tenforde MW, Ujamaa D, Talbot HK, O'Halloran AC, Chai SJ, Sachdev D, Armistead I, Alden NB, Meek J, Yousey-Hindes K, Witt LS, Openo KP, Ryan PA, Monroe ML, Kim S, Nunez VT, Lynfield R, McMahon M, McCahon C, Bleecker M, Barney G, Mahoney K, Tesini BL, Gaitan MA, Ingabire-Smith D, Moran NE, Sutton M, Hendrick A, Schaffner W, Chatelain R, Swain A, Garg S, Bozio CH.   +32 more
europepmc   +1 more source

Comment On: "Association Between Admission Prognostic Nutritional Index and Pulmonary Infection Status in Hospitalized Lung Cancer Patients: A Retrospective Cohort Study" [Letter]. [PDF]

J Inflamm Res
Dan Q.
europepmc   +1 more source

Comparative Clinical Characteristics of ICU and Non-ICU Hospitalized Patients With Human Anaplasmosis. [PDF]

Open Forum Infect Dis
Dumic I, Schultz M, Benny C, Rich J, Shiari A.   +4 more
europepmc   +1 more source