Results 71 to 80 of about 1,081,205 (298)

Evaluation of the Utility of Baseline Echocardiogram in Patients With Standard Risk Precursor B‐Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
Abstract Background A routine baseline echocardiogram is often obtained prior to anthracycline administration in children with cancer. The utility of baseline echocardiogram is unclear in patients with standard risk B‐cell acute lymphoblastic leukemia (SR B‐ALL) as their anthracycline cumulative dose is low.
Ziyad Alrajhi, Alice Pozza, Luc Mertens, Adam Paul Yan, Sarah Alexander   +4 more
wiley   +1 more source

An Epidemiological Study of the Infectious Diseases of Older Adults Hospitalized in Hospitals Affiliated to Birjand University of Medical Sciences, in 2016

Sālmand, 2019
Objectives Older adulthood refers to 65 years or older. In Iran, older people account for 8.5% of the whole population totaling 4.5 million people. Because of the disorders in the immune system, older adults catch infection diseases more frequently. Also,
Khaironnesah Ramezanzadeh, Gholamreza Sharifzadeh, Mahbobeh Saljughi, Mitra Moodi, Azadeh Ibrahimzadeh   +4 more
doaj  

Outcomes of Hydroxychloroquine Usage in United States Veterans Hospitalized with COVID-19

medRxiv, 2020
BACKGROUND: Despite limited and conflicting data on the use of hydroxychloroquine in patients with Covid-19, the U.S. Food and Drug Administration has authorized the emergency use of this drug when clinical trials are unavailable or infeasible ...
J. Magagnoli, S. Narendran, Felipe Pereira, T. Cummings, J. Hardin, S. Sutton, J. Ambati   +6 more
semanticscholar   +1 more source

External Validation of a Widely Implemented Proprietary Sepsis Prediction Model in Hospitalized Patients.

JAMA Internal Medicine, 2021
Importance The Epic Sepsis Model (ESM), a proprietary sepsis prediction model, is implemented at hundreds of US hospitals. The ESM's ability to identify patients with sepsis has not been adequately evaluated despite widespread use.
Andrew Wong, E. Otles, J. Donnelly, A. Krumm, J. McCullough, Olivia DeTroyer-Cooley, J. Pestrue, Marie Phillips, Judy Konye, C. Penoza, Muhammad Ghous, Karandeep Singh   +11 more
semanticscholar   +1 more source

CPX‐351 in High‐Risk Relapsed Pediatric Acute Leukemia: Real‐World Phase 1 Data Establishing the FDA‐Approved Dose

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender, Lauren Pommert, Lori R. Backus, Andrea Bidwell, Courtney Blank, Erin H. Breese, Karen C. Burns, Adam Lane, Lynn H. Lee, Benjamin Mizukawa, Robin E. Norris, Maureen M. O'Brien, Daniel Peck, Christine Phillips, Thomas D. Ryan, Jennifer Young, Michael Absalon, John P. Perentesis   +17 more
wiley   +1 more source

Incidence and Risk Factors of Serious Osteonecrosis in Pediatric Acute Lymphoblastic Leukemia: A CYP‐C Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteonecrosis (ON) is a debilitating complication of acute lymphoblastic leukemia (ALL) therapy. While numerous studies have explored its incidence and associated risk factors, investigations using large‐scale cohorts remain important to characterize ON across heterogeneous populations.
Noémie de Villiers, Chantal Éthier, Caroline Laverdière, Nathalie Alos, Thai Hoa Tran, Marie‐Claude Pelland‐Marcotte   +5 more
wiley   +1 more source

Identification of comprehensive geriatric assessment‐based risk factors for insomnia in elderly Chinese hospitalized patients

Aging Medicine, 2021
Objective Insomnia is a common problem in older persons and is associated with poor prognosis from a functional or clinical perspective. The purpose of this study was to investigate the prevalence of insomnia and identify comprehensive geriatric ...
Rong Liu, Wenchao Shao, Jonathan King‐Lam Lai, Lingshan Zhou, Man Ren, Nianzhe Sun   +5 more
doaj   +1 more source

Prothrombotic autoantibodies in serum from patients hospitalized with COVID-19

Science Translational Medicine, 2020
Some patients with severe COVID-19 develop prothrombotic autoantibodies that are similar to antiphospholipid antibodies found in autoimmune diseases. Casting an autoantibody NET in COVID-19 Patients with severe COVID-19 are at high risk for occlusion of ...
Y. Zuo, S. Estes, R. Ali, Alex A. Gandhi, S. Yalavarthi, Huirong Shi, G. Sule, K. Gockman, J. Madison, M. Zuo, Vinita Yadav, Jintao Wang, Wrenn Woodard, Sean P Lezak, N. Lugogo, Stephanie A. Smith, J. Morrissey, Y. Kanthi, J. Knight   +18 more
semanticscholar   +1 more source

Improving the Evaluation and Management of Transfusion‐Related Iron Overload in Children, Adolescents, and Young Adults Following Cancer Treatment or Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Transfusion‐related iron overload (TRIO) is a late effect of therapy impacting survivors of childhood cancer and hematopoietic stem cell transplantation (HSCT) who receive frequent packed red blood cell (pRBC) transfusions. Surprisingly, there are no accepted guidelines to assist providers in identifying and treating at‐risk ...
Luke Gingell, Allison Close, Guoli Zhou, Troy C. Quigg   +3 more
wiley   +1 more source

Scientific and Standardization Committee communication: Clinical guidance on the diagnosis, prevention, and treatment of venous thromboembolism in hospitalized patients with COVID‐19

Journal of Thrombosis and Haemostasis, 2020
The novel coronavirus disease of 2019 (COVID-19) pandemic, as declared by the World Health Organization, is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). Cardiovascular disease and, in particular, venous thromboembolism (VTE)
A. Spyropoulos, J. Levy, W. Ageno, J. Connors, B. Hunt, T. Iba, M. Levi, C. Samama, J. Thachil, D. Giannis, J. Douketis   +10 more
semanticscholar   +1 more source