Results 161 to 170 of about 3,530,763 (295)

Comprehensive analysis of extracellular matrix remodelling via cyclophilin inhibition in human models of alcohol‐related liver fibrosis

British Journal of Pharmacology, EarlyView.
Background and Purpose Chronic liver disease and hepatic fibrosis constitute a threat to global health. Clinical translation of preclinical research has been limited, highlighting an urgent need for novel treatments. Cyclophilin inhibitors have shown beneficial effects in liver disease; however, the underlying mechanism of action and the effect across ...
Una Rastovic, Sara Campinoti, Lai Wei, Bruna Almeida, Sergio Francesco Bozzano, Ramin Amiri, Nicola Harris, Omolola Ajayi, Tsin Shue Koay, Caoimhe Kerins, Fiona N. Kenny, Ane Zamalloa, Lissette Adofina, Rosa Miquel, Yoh Zen, Parthi Srinivasan, Krishna Menon, Nigel Heaton, Camilla Luni, Eileen Gentleman, Tanya Shaw, Daren Ure, Shilpa Chokshi, Luca Urbani, Elena Palma   +24 more
wiley   +1 more source

Ask, and it shall be given you - individual patient data and code availability for randomised controlled trials submitted for publication. [PDF]

Anaesthesia
Bramley P.
europepmc   +1 more source

A 14‐Gene Panel for Predicting Colorectal Cancer Recurrence Using Circulating Tumor DNA in Different Testing Conditions

Cancer Science, EarlyView.
As circulating tumor DNA has emerged as a promising minimal residual disease biomarker, we evaluated circulating tumor DNA detection using a sensitive, targeted 14‐gene panel, the Sysmex Plasma‐Safe‐SeqS colorectal cancer assay, in resectable colorectal cancer cases.
Yuichi Hisamatsu, Koji Ando, Kensuke Kudo, Ryota Nakanishi, Tetsuro Kawazoe, Yoko Zaitsu, Tetsuya Kusumoto, Taishi Hata, Yoshinori Kagawa, Tomoharu Yoshizumi, Naoko Ashida, Hayato Niiro, Takashi Hirose, Eiji Oki   +13 more
wiley   +1 more source

Computerized Clinical Decision Support to Prevent Venous Thromboembolism among Hospitalized Patients: Proximal Outcomes from a Multiyear Quality Improvement Project

Journal for Healthcare Quality, EarlyView., 2014
Abstract Despite venous thromboembolism (VTE) policy initiatives, gaps exist between guidelines and practice. In response, hospitals implement clinical decision support (CDS) systems to improve VTE prophylaxis. To assess the impact of a VTE CDS on reducing incidence of VTE, this study used a pretest/posttest, longitudinal, cohort design incorporating ...
Robert C. Amland, Bonnie B. Dean, Hsing‐Ting Yu, Hugh Ryan, Timothy Orsund, Jeffrey L. Hackman, Shauna R. Roberts   +6 more
wiley   +1 more source

An openEHR based infection control system to support monitoring of nosocomial bacterial clusters and contacts. [PDF]

NPJ Digit Med
Biermann P, Baier C, Vietor AC, Zacher B, Baumgartl T, von Landesberger T, Behnke M, Storck M, Petzold M, Kaase M, HiGHmed lnfection Control Study Group, Schlüter D, Marschollek M, Scheithauer S, Wulff A.   +14 more
europepmc   +1 more source

Making Accurate Judgements in Child Welfare: Comparing ChatGPT With Qualified Social Workers

Child &Family Social Work, EarlyView.
ABSTRACT This study compares the judgemental accuracy of child and family social workers (n = 581) with ChatGPT, a generative AI model. Using 12 anonymized referrals, participants were asked predictive questions to evaluate accuracy through Brier scores. ChatGPT outperformed the average social worker on 11 of the 12 referrals, though the difference was
David Wilkins, Verity Benett
wiley   +1 more source

Factors Affecting the Efficacy of Airflowing in Cleaning Implant Surfaces in a Surgical Peri‐Implantitis Treatment Simulation—A Laboratory Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objective To evaluate, in a simulation of surgical peri‐implantitis treatment, the impact of type of handpiece, device settings, and instrumentation time on the efficacy of airflowing in cleaning the implant surface, depending on the type of bone defect and implant surface.
Andreas Stavropoulos, Ahmad Al Said, Ola Mustafa, Loukia M. Spineli, Patrick Heimel, Kristina Bertl   +5 more
wiley   +1 more source

'A tough nut to crack': inconsistent standards as roadblocks to data interoperability of health information systems in public hospitals in the Gauteng Province of South Africa. [PDF]

Oxf Open Digit Health
Chuma KG.
europepmc   +1 more source

The real‐world relationship between naltrexone/bupropion treatment and weight loss in Canada: A retrospective chart review

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary This study examined the change in weight at 6 months of naltrexone/bupropion (NB), a combination pharmacological therapy for weight management, in real‐world practice in Canada. The study was conducted through an observational, retrospective, single‐arm chart review of adult patients who attended the Wharton Medical Clinic in Ontario, Canada ...
Sean Wharton, Elham Kamran, Lehana Thabane, Peter Yin, Rebecca Christensen   +4 more
wiley   +1 more source

Patient Health Record Smart Network Challenges and Trends for a Smarter World. [PDF]

Sensors (Basel)
Vicoveanu D, Gherman O, Șoldănescu I, Lavric A.   +3 more
europepmc   +1 more source