Results 171 to 180 of about 44,030 (233)

Maternal Anaemia and Congenital Heart Disease in Offspring: A Case–Control Study Using Linked Electronic Health Records in the United Kingdom

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 132, Issue 8, Page 1139-1146, July 2025.
ABSTRACT Objective Assessment of whether maternal anaemia in early pregnancy is associated with offspring congenital heart disease (CHD). Design Matched case–control study. Setting January 1998–October 2020, United Kingdom. Population Women with a haemoglobin measurement in the first 100 days of pregnancy and a CHD‐diagnosed child.
Manisha Nair, Cynthia W. Drakesmith, Margaret Smith, Clare R. Bankhead, Duncan B. Sparrow   +4 more
wiley   +1 more source

A systematic methodological evaluation of sepsis guidelines: Protocol for quality assessment and consistency of recommendations

Acta Anaesthesiologica Scandinavica, Volume 69, Issue 6, July 2025.
Abstract Background Sepsis is a leading cause of mortality worldwide, characterized by a dysregulated host response to infection. Despite the development of multiple clinical practice guidelines (CPGs) to standardize sepsis management, substantial variability exists in methodological quality and key clinical recommendations.
Marwa Amer, Morten Hylander Møller, Anders Granholm, Haifa F. Alotaibi, Shadan AlMuhaidib, Zainab Al Duhailib, Amr Arafat, Michelle S. Chew, Marius Rehn, Martin Ingi Sigurðsson, Maija‐Liisa Kalliomäki, Klaus T. Olkkola, Ville Jalkanen, Wojciech Szczeklik, Hassan M. Alshaqaq, Kimberley Lewis, Kallirroi Laiya Carayannopoulos, Kimia Honarmand, Dipayan Chaudhuri, Mustafa Alquraini, Yasser S. Amer, Fayez Alshamsi, Waleed Alhazzani   +22 more
wiley   +1 more source

The health economics of insulin therapy: How do we address the rising demands, costs, inequalities and barriers to achieving optimal outcomes

Diabetes, Obesity and Metabolism, Volume 27, Issue S5, Page 24-35, July 2025.
Abstract The health economic value of insulin is usually expressed within a cost‐effectiveness framework providing an estimated incremental cost per quality‐adjusted life year (QALY) gained. Insulin clinical trials adopt a treat‐to‐target design in which both intervention and control arms aim to achieve similar levels of glycaemic control thereby ...
Phil McEwan, Marc Evans
wiley   +1 more source

Identification of a Novel Mutation in the SERPINE1 Gene Causing Clinical Hyperfibrinolysis in English Springer Spaniel Dogs

Journal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT Background A 7‐month‐old female spayed English Springer Spaniel (ESS) was evaluated for spontaneous hemoperitoneum. Hyperfibrinolysis was identified on thromboelastography. Hypothesis/Objectives To identify a genetic mutation causing congenital hyperfibrinolysis in the proband and evaluate the prevalence of the mutation in the ESS breed ...
Kelley Kilpatrick, Jonah N. Cullen, Farah F. Almeer, LeeAnn Higgins, Todd Markowski, Marjory Brooks, Steven G. Friedenberg, Molly Racette   +7 more
wiley   +1 more source

Bringing Child Health Closer to Families: Lessons From a Family MUAC Intervention in Urban and Rural South Africa

Maternal &Child Nutrition, Volume 21, Issue 3, July 2025.
ABSTRACT Mid‐upper‐arm circumference measurement (MUAC) is a simple, cost‐effective approach to identify wasting in children. The Family MUAC intervention supported community health workers (CHWs) to mentor mothers and child caregivers to measure their children's MUAC at home.
Christiane Horwood, Sphindile Mapumulo, Silondile Luthuli, Zandile Kubeka, Nireshnee Reddy, Gilbert Tshitaudzi, Tshifiwa Mashamba, Nomonde Motshoeneng, Lyn Haskins   +8 more
wiley   +1 more source

Controlling and Promoting Quality in Medical Care [PDF]

, 1970
Roemer, Milton I.
core   +1 more source

Intra‐ and Interobserver Variability of Acute Food–Induced Reactions During Confocal Laser Endomicroscopy: An International Multicenter Validation Study

Neurogastroenterology &Motility, Volume 37, Issue 7, July 2025.
This multicentric international study investigated the intra‐ and interobserver variability of confocal laser endomicroscopy in assessing acute food–induced mucosal reactions. Agreement between real‐time and blinded post hoc assessments was moderate to substantial, and agreement between post hoc assessors was substantial. Created in BioRender. Balsiger‐
Lukas Michaja Balsiger, Tom van Gils, Yaser Hatem, Amanda Blomsten, Karlien Raymenants, Cedric Van de Bruaene, Leila Juvyns, Johann P. Hreinsson, Tim Vanuytsel, Hans Törnblom, Christian Sina, Magnus Simren, Jan Tack   +12 more
wiley   +1 more source

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

Molecular Oncology, Volume 19, Issue 6, Page 1797-1810, June 2025.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen, Pieter‐Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W. J. de Leng, Anne M. L. Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst‐Jan M. Speel, Wilfred F. J. van IJcken, Brigitte Maes   +17 more
wiley   +1 more source

What is reproducibility in artificial intelligence and machine learning research?

AI Magazine, Volume 46, Issue 2, Summer 2025.
Abstract In the rapidly evolving fields of artificial intelligence (AI) and machine learning (ML), the reproducibility crisis underscores the urgent need for clear validation methodologies to maintain scientific integrity and encourage advancement. The crisis is compounded by the prevalent confusion over validation terminology.
Abhyuday Desai, Mohamed Abdelhamid, Nakul R. Padalkar   +2 more
wiley   +1 more source

Dosimetric effect of silicone‐based gel on skin surface during volumetric modulated arc therapy for breast cancer

Journal of Applied Clinical Medical Physics, Volume 26, Issue 6, June 2025.
Abstract Purpose This study aims to quantify and compare the dosimetric effects of varying thicknesses of StrataXRT, a silicone‐based gel, and other topical agents on the skin surface during volumetric modulated arc therapy (VMAT) for breast cancer.
Tenyoh Suzuki, Shingo Ohira, Mami Ogita, Takeshi Ohta, Yuki Nozawa, Masanari Minamitani, Takuya Hayashi, Shigeki Saegusa, Toshikazu Imae, Tsuyoshi Ueyama, Atsuto Katano, Hideomi Yamashita, Weishan Chang, Keiichi Nakagawa   +13 more
wiley   +1 more source