Results 311 to 320 of about 9,187,129 (361)

Activation of HTR2B Suppresses Osteosarcoma Progression through the STAT1‐NLRP3 Inflammasome Pathway and Promotes OASL1+ Macrophage Production to Enhance Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
Activation of HTR2B suppresses osteosarcoma progression through the STAT1‐NLRP3 inflammasome pathway and promotes OASL1+ Macrophage production to enhance anti‐tumor immunity. Abstract Osteosarcoma is a primary malignant bone tumor originating from mesenchymal tissue, and associated with poor prognosis.
Zhen Huang   +7 more
wiley   +1 more source

Single‐Cell Analysis Clarifies Pathological Heterogeneity in Tenosynovial Giant Cell Tumor and Identifies Biomarkers for Predicting Disease Recurrence

open access: yesAdvanced Science, EarlyView.
MP3 tumor cells, a specific subpopulation of tumor cells in D‐TGCT, regulated the differentiation of CD34+ Fbs into MMP3+ Fbs and APOE+ Fbs through COL6A3 − (ITGAV + ITGB8) interaction. APOE+ Fbs activated IL‐1B+CCL20+ Mφs through the CXCL12/CXCR4 axis. IL‐1B+CCL20+ Mφs and MMP3+ Fbs participated in the local invasion of D‐TGCT.
Yubin Xie   +15 more
wiley   +1 more source

A multisite inventory study of neonatal syringe pumps in Zambia. [PDF]

open access: yesMatern Health Neonatol Perinatol
Norton O   +4 more
europepmc   +1 more source

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

open access: yesAdvanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen   +12 more
wiley   +1 more source

Non‐Invasive Tumor Budding Evaluation and Correlation with Treatment Response in Bladder Cancer: A Multi‐Center Cohort Study

open access: yesAdvanced Science, EarlyView.
This study introduces a deep learning model that predicts tumor budding (TB) status in bladder cancer through the analysis of CT images. The model effectively identifies patients with high TB status, correlating with poorer prognosis and reduced responsiveness to neoadjuvant chemoimmunotherapy. This tool offers significant potential to inform prognosis
Xiaoyang Li   +21 more
wiley   +1 more source

Sleep quality and associated factors among people with asthma at public hospitals in east gojjam zone, North West Ethiopia, 2022. [PDF]

open access: yesPLoS One
Gete M   +12 more
europepmc   +1 more source

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