Results 91 to 100 of about 13,331,196 (287)

PREVALENCE, PATTERN, AND RISK FACTORS FOR URINARY INCONTINENCE AMONG WOMEN IN A LOW-RESOURCE SETTING [PDF]

Sanamed
Introduction: Urinary incontinence (UI) is a common but under-reported condition among women in low-resource settings. The prevalence and pattern of UI, as well as associated risk factors must be examined to inform appropriate health interventions.
Okesina S. Bolanle, Fehintola O. Akintunde, Raji O Hadijat, Abdur-Rahim Z. Foyeke, Ajiboye D. Akinyosoye, Ayegbusi E. Oluwole   +5 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Adherence to Practice Guidelines in the Implementation of Emergency Obstetric and Newborn Care in Referral Hospitals in Osun State, Nigeria

SAGE Open Nursing
Introduction While practice guidelines support clinical decision-making for optimal patient outcomes, there is often nonadherence to practice guidelines in implementing evidence-based interventions.
Abiola Olubusola Komolafe, Aanuoluwapo Omobolanle Olajubu, Omotade Adebimpe Ijarotimi, Oluwasayo Bolarinwa Ogunlade, Adekemi Eunice Olowokere, Omolola Oladunni Irinoye   +5 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Hospital Community Benefits After the ACA: The Emerging Federal Framework [PDF]

, 2011
Outlines the federal framework on requirements for hospitals to provide community benefit activities in exchange for tax-exempt status under the 2010 healthcare reform, including community health needs assessments; state policy options; and ...
Avery L. R. Brow, Carl H. Mueller, Charles Milligan, Cynthia L. Boddie-Willis, Donna C. Folkemer, Laura A. Spicer, Martha H. Somerville   +6 more
core  

Mortality Changes Associated with Mandated Public Reporting for Sepsis. The Results of the New York State Initiative

American Journal of Respiratory and Critical Care Medicine, 2018
Rationale: In 2013, the New York State Department of Health (NYSDOH) began a mandatory state‐wide initiative to improve early recognition and treatment of severe sepsis and septic shock.
M. Levy, F. Gesten, G. Phillips, Kathleen M. Terry, C. Seymour, H. Prescott, M. Friedrich, T. Iwashyna, T. Osborn, S. Lemeshow   +9 more
semanticscholar   +1 more source

Liquid Hydroxyurea (Xromi) for Children With Sickle Cell Anemia: A New Solution Compounding Existing Problems

Pediatric Blood &Cancer, EarlyView.
Alexandra Power‐Hays, Charles T. Quinn
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Factors Associated with the Uptake of Covid-19 Vaccines Among Adult Residents of Selected Communities in South-West Nigeria

Nigerian Frontline Medicine Journal
Background: The rate of uptake of COVID-19 vaccines varies from one region of Nigeria to another and is influenced by different ...
Ibrahim S. Bello, Temitope O. Olajubu, Oluwasina T. Salami, Olawaseun C, Asaleye, Shekinah Y. Williams   +4 more
doaj  

Georgia’s Rural Hospital Closures: The Common-Good Approach to Ethical Decision-Making

Journal of the Georgia Public Health Association, 2016
Background: Critical access hospitals provide several essential services to local communities. Along with the functions associated with providing necessary medical care, they also offer employment opportunities and other economic benefits to the ...
Randi Bastian, Marcus Garner, John Barron, Emmanuel Akowuah, William Mase   +4 more
doaj   +1 more source