Results 251 to 260 of about 3,648,409 (294)

How senior leaders support innovations in large learning health systems: Insights from United States Veterans Health Administration national program office leaders

open access: yesLearning Health Systems, EarlyView.
Abstract Background The U.S. Veterans Health Administration (VHA) formed an Innovation Ecosystem that develops and disseminates innovative practices to enhance Veterans' health. Support of senior leadership and their perception of the innovation process is key to the Ecosystem's success.
Jaifred Christian F. Lopez   +17 more
wiley   +1 more source

Disentangling informing participants from obtaining their consent

open access: yesLearning Health Systems, EarlyView.
Abstract Introduction Pragmatic clinical trials conducted in the context of routine care frequently satisfy the regulatory criteria for a waiver of research consent. When they do, investigators and Institutional Review Boards might assume that there is no reason to communicate any information regarding the study to participants.
Patricia Pearl O'Rourke   +15 more
wiley   +1 more source

Development and validation of a computable phenotype for adolescent idiopathic scoliosis

open access: yesLearning Health Systems, EarlyView.
Abstract Introduction There remains a lack of understanding of the etiology and treatment effectiveness for Adolescent idiopathic scoliosis (AIS). The objective of this study was to develop and validate a computable phenotype for patients with AIS to facilitate rapid learning through large‐scale observational research using real‐world data.
Sarah B. Floyd   +6 more
wiley   +1 more source

Learning Health System study designs for the evaluation of workforce interventions to cultivate eudaimonia (flourishing)

open access: yesLearning Health Systems, EarlyView.
Abstract Background The Learning Health System (LHS) framework is designed to enhance healthcare by systematically integrating internal data and external evidence to promote quality, safety, and efficiency, aligning science, informatics, incentives, and culture for continuous improvement, innovation, and equity.
Michael R. Cauley   +8 more
wiley   +1 more source

CDC's Core Elements to promote diagnostic excellence. [PDF]

open access: yesDiagnosis (Berl)
Morgan DJ   +5 more
europepmc   +1 more source

A Randomized, Double‐Blind, Placebo Controlled, Crossover Trial of incobotulinumtoxinA Treatment for Upper Limb Tremor

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Proximal upper limb tremor is a common, functionally disabling condition. Medical therapy is often ineffective. IncobotulinumtoxinA can significantly improve tremor with minimal adverse effects. Objectives We aimed to compare clinical, functional, and quality of life measures in patients with proximal upper limb tremor following ...
Sai A. Nagaratnam   +10 more
wiley   +1 more source

Neuronal α‐Synuclein Disease Stage Progression over 5 Years

open access: yesMovement Disorders, EarlyView.
Abstract Background Neuronal α‐synuclein disease (NSD) is defined by the presence of an in vivo biomarker of neuronal alpha‐synuclein (n‐asyn) pathology. The NSD integrated staging system (NSD‐ISS) for research describes progression across the disease continuum as stages 0 to 6.
Tanya Simuni   +205 more
wiley   +1 more source

Israel should build capacity in implementation science. [PDF]

open access: yesIsr J Health Policy Res
Rose AJ, Spitzer S, Ellen ME.
europepmc   +1 more source

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