Results 71 to 80 of about 4,135,653 (363)

Artificial Intelligence in Systemic Sclerosis: Clinical applications, challenges, and future directions

open access: yesArthritis Care &Research, Accepted Article.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos   +2 more
wiley   +1 more source

Habituation of parasympathetic-mediated heart rate responses to recurring acoustic startle

open access: yesFrontiers in Psychology, 2014
Startle habituation is a type of implicit and automatic emotion regulation. Diminished startle habituation is linked to several psychiatric or neurological disorders.
Kuan-Hua eChen   +10 more
doaj   +1 more source

Microfluidic Modeling of Macrophage‐Induced Cardiac Inflammation Using NF‐κB Reporter Cardiomyocytes

open access: yesAdvanced Healthcare Materials, EarlyView.
A cardiac inflammation model was developed to enable real‐time analysis of macrophage‐cardiomyocyte interactions using NF‐κB‐reporter cardiomyocytes and a microfluidic co‐culture system. A MATLAB‐based model was implemented to optimize cell density and medium resupply based on TNFα diffusion kinetics. Activation thresholds and stress responses in NF‐κB‐
Chao Liu   +6 more
wiley   +1 more source

Health disparities in chronic liver disease

open access: yesHepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian   +3 more
wiley   +1 more source

Biomimetic Copper Nanoparticles Coated with ACE2‐Overexpressing Membranes for Selective SARS‐CoV‐2 Neutralization and Disinfection

open access: yesAdvanced Healthcare Materials, EarlyView.
By fusing ACE2‐overexpressing membrane‐integrated liposome (MIL) with copper nanoparticles, the biomimetic Cu@MIL nanostructures were created that directly hijack the SARS‐CoV‐2 entry pathway. These particles combine potent virus‐targeting precision with intrinsic antiviral activity, achieving rapid neutralization and disinfection.
Pooja Aich   +8 more
wiley   +1 more source

Adverse events in veterans affairs inpatient psychiatric units: Staff perspectives on contributing and protective factors. [PDF]

open access: yes, 2017
OBJECTIVES: This study sought to identify risk factors and protective factors in hospital-based mental health settings in the Veterans Health Administration (VHA), with the goal of informing interventions to improve care of persons with serious mental ...
Cullen, Sara W.   +4 more
core   +1 more source

Hospital preparedness for COVID-19 pandemic: experience from department of medicine at Veterans Affairs Connecticut Healthcare System

open access: yesPostgraduate medicine, 2020
The 2019–2020 pandemic Coronavirus Disease 2019 (COVID-19) has inundated hospital systems globally, as they prepare to accommodate surge of patients requiring advanced levels of care.
Shaili Gupta, D. Federman
semanticscholar   +1 more source

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

open access: yesAdvanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann   +15 more
wiley   +1 more source

Acute perforated appendicitis due to metastatic small-cell lung cancer

open access: yesThe Turkish Journal of Gastroenterology, 2019
Cite this article as: Keramidaris D, Oikonomou C, Theodorolea K, Mohamed T, Gourgiotis S. Acute perforated appendicitis due to metastatic small-cell lung cancer. Turk J Gastroenterol 2019; 30(11): 993-4.
Dimitrios Keramidaris   +4 more
doaj   +1 more source

Advancing Patient Safety in the U.S. Department of Veterans Affairs [PDF]

open access: yes, 2011
As part of a systemwide transformation, the VA formed its National Center for Patient Safety to foster an organizational culture of safety within its nationwide network of hospitals and outpatient clinics.
Deborah Chase, Douglas McCarthy
core  

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