Results 141 to 150 of about 1,254,901 (269)

Physicians' Perceptions of Prescribing in Pregnancy and Package Inserts: A Survey of General and Hub Hospitals in Japan. [PDF]

Clin Transl Sci
Goto M, Yakuwa N, Murashima A.
europepmc   +1 more source

Florence Nightingale’s Influence on Hospital Design, Hospitalism, Hospital Diseases, and Hospital Architects [PDF]

HERD: Health Environments Research & Design Journal, 2020
openaire   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Exploring the Interface Between International Nongovernmental Organizations and Local Vietnamese Hospitals in Cleft Care. [PDF]

Plast Reconstr Surg Glob Open
Le T, Nguyen LN, Berry CE, Dinh AM, Klaudt-Moreau J, Doan TC, Runyan CM, Nguyen PD.   +7 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Antibiotic stewardship in hospital outpatient departments: a qualitative study of alignment with existing guidance. [PDF]

Antimicrob Steward Healthc Epidemiol
Chitavi SO, Buckel WR, Kohut M, Braun B, Zetts R, Hyun D.   +5 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Enhancing perinatal care in Rwanda: building quality improvement into system strengthening. [PDF]

BMJ Paediatr Open
Tuyisenge L, Habonimana JP, Nsengiyumva A, Cyiza FR, Manzi E, Desie S, Pledge A, McMurtrie S, Muzard-Banes C, Bontoux M, Taylor S.   +10 more
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Examining Canadian Hospitals’ Support for Planetary Health Through the Implementation of Green Teams and Sustainability Offices

Journal of Healthcare Leadership
Maya R Kalogirou, Jennifer Baumbusch School of Nursing, University of British Columbia, Vancouver, BC, CanadaCorrespondence: Maya R Kalogirou, University of Alberta, College of Health Sciences, Faculty of Nursing, Edmonton Clinic Health Academy (ECHA ...
Kalogirou MR, Baumbusch J
doaj