Results 191 to 200 of about 1,581,517 (315)

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

In-hospital outcomes of adults with diabetes treated in certified vs. non-certified hospitals: a nationwide analysis of German DRG statistics. [PDF]

Front Health Serv
Auzanneau M, Fritsche A, Eckert AJ, Seidel-Jacobs E, Heni M, Lanzinger S.   +5 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Performance of the Dutch Pediatric Early Warning Score: a nationwide study in academic, large teaching and general hospital contexts, using real-world data. [PDF]

BMJ Paediatr Open
Stevens J, de Groot J, Hoogervorst-Schilp J, Willemsen MA, Fuijkschot J.   +4 more
europepmc   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Efficiency of Hospitals in the Czech Republic

The paper estimates cost efficiency of 99 general hospitals in the Czech Republic during 2001-2008 using Stochastic Frontier Analysis. We estimate a baseline model and also a model accounting for various inefficiency determinants.
Jana Procházková, Lenka Šťastná
core  

Current state and potential of hospitals for automated healthcare-associated infection surveillance: data from 24 European countries, 2022 to 2023. [PDF]

Euro Surveill
Rüther FD, Guedes M, Presterl E, Suetens C, Plachouras D, van Mourik MS, van Rooden S, ECDC PPS study group on automated surveillance of HAIs, Collaborators.   +8 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

EFFICIENCY ANALYSIS OF HOSPITALS IN THE GREAT PLAINS: AN URBAN-RURAL COMPARISON

This study examined the efficiency of a sample of hospitals in the Great Plains using a nonparametric approach. Technical efficiency was less than either allocative or scale efficiency.
Featherstone, Allen M., Toodi, Bhaskar, Young, Ronald C.   +2 more
core  

National survey of protocols for day-case hip and knee arthroplasty in the UK. [PDF]

Bone Jt Open
Edwards TA, Large J, French JMR, Evans JT, Reed MR, Whitehouse MR, Day Case Collaborative, Ng ABY, Hosea A, Pradhan A, Date A, Charalambous A, Hunt A, Nakhla A, Firth AM, Metry A, Bolland BJ, Aliker C, Navaratnam DM, Waugh D, Ojelade E, Morriss F, Chadalavada G, Slade G, Higgins G, Neal-Smith G, Umer HM, Noone H, Rankin I, Muhammad I, Ahmed I, Morris J, Roberts J, Hill J, Quayle J, Topping J, Heylen J, Howard J, Moreau J, Roope J, Cumberworth J, Logishetty K, Hogan K, Khilla K, Syam K, Patel K, Kaushik Dash K, Sinan L, Jenner L, Girling L, Choi M, Andrews M, Gibby M, Petrie M, Wilson M, Mubashir Siddiqui M, Bhaskara NV, Flannery O, Kabariti R, Ashour R, Sinnerton R, Azeez S, Everett SJ, Miller S, Hermena S, Mehta S, Bannagham S, Mannan S, Khaleeq T, Maunganidze T, Petheram T, Ross Fraser T, Ng Z.   +72 more
europepmc   +1 more source