Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr+5 more
wiley +1 more source
Regional disparities, dynamic evolution, and spatial spillover effects of medical resource allocation efficiency in TCM hospitals. [PDF]
Wang Z, Li Z, Xie R.
europepmc +1 more source
ADDENBROOKE'S HOSPITAL, CAMBRIDGE: OVARIOTOMY: TETANUS DURING RECOVERY: DEATH [PDF]
G. M. Humphry
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High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson+5 more
wiley +1 more source
Effects of DRG/DIP payment reform on hospital pharmacy administration and pharmaceutical services in China: a multicenter cross-sectional study. [PDF]
Wang X+6 more
europepmc +1 more source
INCIDENCE AND TREATMENT OF ENTAMOEBA HISTOLYTICA INFECTION AT WALTON HOSPITAL [PDF]
Clifford Dobell
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Beyond p‐values: Assessing clinical significance in acupuncture research
Abstract In acupuncture randomized controlled trials (RCTs), the proper interpretation of results requires a thorough understanding of key statistical concepts such as p‐value, effect size, and the minimal clinically important difference (MCID). This paper explores the relationships among these metrics and their implications for assessing the clinical ...
Changzhen Gong
wiley +1 more source
Evidence-based intrapartum care practice and associated factors among obstetric care providers in Jimma Zone public hospitals, southwest Ethiopia: A cross-sectional study. [PDF]
Wakjira D+3 more
europepmc +1 more source
THE INCIDENCE OF ACUTE RHEUMATIC FEVER AT BELLEVUE HOSPITAL [PDF]
ALEXANDER LAMBERT
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