Results 151 to 160 of about 3,731,631 (387)

A comprehensive collection of systems biology data characterizing the host response to viral infection [PDF]

, 2014
Brian D. Aevermann, Brett E Pickett, Sanjeev Kumar, Edward B. Klem, Sudhakar Agnihothram, Peter S. Askovich, Armand Bankhead, Meagen Bolles, Victoria Carter, Jean Chang, Therese RW Clauss, Pradyot Dash, Alan H. Diercks, Amie J. Eisfeld, Amy Ellis, Shufang Fan, Martin T. Ferris, Lisa E. Gralinski, Richard Green, Marina A. Gritsenko, Masato Hatta, Robert A. Heegel, Jon Jacobs, Sophia Jeng, Laurence Josset, Shari M. Kaiser, Sara Kelly, G. Lynn Law, Chengjun Li, Jiangning Li, Casey Long, Maria L. Luna, Melissa M. Matzke, Jason McDermott, Vineet D. Menachery, Thomas Metz, Hugh Mitchell, Matthew Monroe, Garnet Navarro, Gabriele Neumann, Rebecca Podyminogin, Samuel Purvine, Carrie M. Rosenberger, Catherine J. Sanders, Athena Schepmoes, Anil Shukla, Amy Sims, Pavel Sova, Vincent C. Tam, Nicolas Tchitchek, Paul G. Thomas, Susan C. Tilton, Allison L. Totura, Jing Wang, Bobbie‐Jo Webb‐Robertson, Ji Wen, Jeffrey M. Weiss, Feng Yang, Boyd L. Yount, Qibin Zhang, Shannon K. McWeeney, Richard Smith, Katrina M. Waters, Yoshihiro Kawaoka, Ralph S. Baric, Alan Aderem, Michael G. Katze, Richard H. Scheuermann   +67 more
openalex   +1 more source

Systems biology of virus-host signaling network interactions

BMB Reports, 2012
Viruses have evolved to manipulate the host cell machinery for virus propagation, in part by interfering with the host cellular signaling network. Molecular studies of individual pathways have uncovered many viral host-protein targets; however, it is difficult to predict how viral perturbations will affect the signaling network as a whole.
Qiong Xue, Kathryn Miller-Jensen
openaire   +4 more sources

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

SURVEILLANCE OF β-LACTAMASE GENES OF SALMONELLA FROM CHICKEN IN WET MARKETS OF METRO MANILA, PHILIPPINES

Biotropia: The Southeast Asian Journal of Tropical Biology
Article Highlights - blaCTX-M gene in 24.7% while blaTEM gene in 11.2% of Salmonella isolates. - Coexistence of blaCTX-M groups II and IV in all blaCTX-M-positive isolates.
Miles Madayag, Rance Derrick Pavon, Jonah Feliza Mora, Khristine Balaga, Windell Rivera   +4 more
doaj   +1 more source

Occurrence of the Old World bug Megacopta cribraria (Fabricius) (Heteroptera: Plataspidae) in Georgia: a serious home invader and potential legume pest [PDF]

, 2010
Specimens of Megacopta cribraria (Fabricius) were collected in northern Georgia in late October 2009, where they were invading homes in large numbers.
Ames, Lisa M., Eger, Joseph E., Jr., Halbert, Susan E., Jenkins, Tracie M., Rider, D. A., Suiter, Daniel R.   +5 more
core  

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Drosophila symbionts in infection: when a friend becomes an enemy

Infection and Immunity
The insect microbiome is comprised of extracellular microbial communities that colonize the host surfaces and endosymbionts that reside inside host cells and tissues.
Yi Yu, Igor Iatsenko
doaj   +1 more source