Results 151 to 160 of about 652,566 (312)

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Biology and control of currant lettuce aphid nasonovia ribisnigri [PDF]

There is a consensus that the development of successful Integrated Pest Management strategies requires a detailed understanding of pest biology. In the case of the currant lettuce aphid (Nasonovia ribisnigri), an economically important pest aphid of ...
Hough, Gemma L.
core  

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Insight into immunoregulatory and neuromodulatory capability of Bacteroides cellulosilyticus and Bacteroides xylanisolvens human gut microbiota isolates

Scientific Reports
Alterations in the abundance of Bacteroides species are linked to the disruption of the intestinal epithelial barrier and chronic inflammation and has been increasingly recognized as a factor in the development of neurological and neuropsychiatric ...
Miroslav Dinić, Jelena Đokić, Stefan Jakovljević, Emilija Brdarić, Hristina Mitrović, Aleksandar Bisenić, Dušan Radojević, Svetlana Soković Bajić, Sergej Tomić, Nataša Golić   +9 more
doaj   +1 more source

Host Biology and Anthropogenic Factors Affect Hepadnavirus Infection in a Neotropical Bat. [PDF]

Ecohealth, 2019
Hiller T, Rasche A, Brändel SD, König A, Jeworowski L, Teague O'Mara M, Cottontail V, Page RA, Glebe D, Drexler JF, Tschapka M.   +10 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Mi Casa es Su Casa: how an intracellular symbiont manipulates host biology. [PDF]

Environ Microbiol, 2017
Bhattacharya T, Newton ILG.
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Host biology and environmental variables differentially predict flea abundances for two rodent hosts in a plague-relevant system. [PDF]

Int J Parasitol Parasites Wildl, 2019
Hammond TT, Hendrickson CI, Maxwell TL, Petrosky AL, Palme R, Pigage JC, Pigage HK.   +6 more
europepmc   +1 more source