Results 41 to 50 of about 172,901 (216)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Infection of Cypriniform Fishes with Argulus coregoni (Crustacea: Branchiura: Argulidae) in a Low-elevation Stream, Central Japan

Species Diversity
Recent studies have reported that salmonids and ayu Plecoglossus altivelis altivelis (Temminck and Schlegel, 1846), both of which are salmoniform fishes, serve as important hosts for Argulus coregoni Thorell, 1864. These studies found the parasite in the
Kazuya Nagasawa, Hiroyuki Nishimura
doaj   +1 more source

Different host plant utilization ability of two closely related Melitaea species (Lepidoptera: Nymphalidae)

European Journal of Entomology, 2015
In natural systems plant-insect interactions are influenced by several factors. For instance plants could be characterised by the presence of defensive chemicals and herbivores are forced to evolve resistance against them.
János P. TÓTH, Judit BERECZKI, Zsolt VÉGVÁRI, Edit JUHÁSZ, Zoltán VARGA   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Argulus coregoni (Crustacea: Branchiura: Argulidae) Parasitic on a Freshwater Minnow Opsariichthys platypus (Cypriniformes: Xenocyprididae) in a Low-Elevation Stream in Kyushu, Western Japan

Species Diversity
An adult female of Argulus coregoni Thorell, 1864 was collected from the operculum of a freshwater minnow Opsariichthys platypus (Temminck and Schlegel, 1846) (Cypriniformes: Xenocyprididae) at 15 m elevation in a stream in Oita Prefecture, Kyushu ...
Kazuya Nagasawa, Naoki Miyajima
doaj   +1 more source

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi, Akito Kawachi, Dan Tomomasa, Eri Watanabe, Yuji Fujita, Yuya Sato, Masahiro Sekiguchi, Kentaro Watanabe, Moe Hidaka, Akihiro Hoshino, Takahiro Kamiya, Masatoshi Takagi, Hirokazu Kanegane, Motohiro Kato   +13 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Argulus coregoni (Crustacea: Branchiura: Argulidae) Parasitic on a Dark Chub Nipponocypris temminckii (Cypriniformes: Xenocyprididae) in a Stream, Central Japan, with a List of Its Known Hosts in East Asia

Species Diversity
An adult male specimen of Argulus coregoni Thorell, 1864 was collected from the body surface of a dark chub Nipponocypris temminckii (Temminck and Schlegel, 1846) at 15 m elevation in a small stream in central Japan.
Kazuya Nagasawa, Ryu Uchiyama, Ko Tomikawa   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Occurrence and Morphology of Argulus coregoni (Crustacea: Branchiura: Argulidae) on Three Species of Fishes in Three Orders (Acipenseriformes, Cypriniformes, and Salmoniformes) Reared at a Fish Hatchery in Central Japan

Species Diversity
Adults of both sexes of Argulus coregoni Thorell, 1864 were collected from the body surface of bester [a hybrid of beluga Huso huso (Linnaeus, 1758) × sterlet sturgeon H. ruthenus (Linnaeus, 1758)], common carp Cyprinus carpio Linnaeus, 1758, and rainbow
Kazuya Nagasawa, Shigeaki Gorie
doaj   +1 more source