Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis
Advanced Science, EarlyView.Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang +7 more
wiley +1 more source
Spatio-temporal distribution of influencing factors of cardiovascular disease in the United States. [PDF]
Front Public HealthLou W +5 more
europepmc +1 more source
Advanced Science, EarlyView.Morphine activates the excitatory cingulate cortex–intermediate rostrocaudal division of zona incerta (Cg‐ZIm) pathway to drive hyperlocomotion in mice. Inhibiting the Cg‐ZIm pathway attenuates both acute and chronic morphine‐induced hyperlocomotion, while its activation mimics morphine's motor effects.
Chun‐Yue Li +13 more
wiley +1 more source
Unveiling Exciton-Plasmon Polariton Coupling Regions via Polarization-Enhanced Optical Nanoscopy. [PDF]
Adv Sci (Weinh)Joo BC, Park DH, Choi KR, Lee YU.
europepmc +1 more source
Advanced Science, EarlyView.RA of EEAR inhibits TGF‐β1 ubiquitination and changes conformation by target binding TGF‐β1, regulating TGF‐β1/Smad2/3 signaling pathway. Thus it down‐regulated downstream protein expression, inhibited EMT and collagen deposition of ECM, in order to EEAR preventing PF in COPD.
Lingfeng Peng +6 more
wiley +1 more source
Dark Septate Endophytic Fungi Improve Dry Matter Production and Fruit Yield in Ever-Bearing Strawberry (<i>Fragaria × ananassa</i> Duch.) Under High Temperatures. [PDF]
Plants (Basel)Aomura N +6 more
europepmc +1 more source
Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction
Advanced Science, EarlyView.This study explores the role adipose tissue (AT) phenotypes have in determining cardiovascular outcomes in an obesity‐related heart failure with preserved ejection fraction (HFpEF) model. Pharmacological induction of thermogenesis promoted resilience to HFpEF‐induced remodeling of AT and conferred cardioprotection. Surgical and genetic models confirmed
Jordan Jousma +11 more
wiley +1 more source
Plasmon-Exciton Strong Coupling in Low-Dimensional Materials: From Fundamentals to Hybrid Nanophotonic Platforms. [PDF]
Nanomaterials (Basel)Zhao P, Lü C, Sun S, Wu F.
europepmc +1 more source
Abundance of moderate-redshift clusters in the cold plus hot dark matter model [PDF]
, 1994 Yipeng Jing, Li‐Zhi Fang
openalex +1 more source
Enhancing the Ultrasonic Welding of Wood Using 3D Printed Lignin Energy Directors
Advanced Science, EarlyView.Sustainable manufacturing for lightweight structures using ecofriendly materials will be key to reducing material consumption and lowering carbon footprints. Here, an approach is presented to weld wood using ultrasonic vibrations with material at the joint interface to direct energy.
Muhamad Amani +6 more
wiley +1 more source