Results 261 to 270 of about 555,829 (322)

ER‐phagy Activation by AMFR Attenuates Cardiac Fibrosis Post‐Myocardial Infarction via mTORC1 Pathway

Advanced Science, EarlyView.
By catalyzing FAM134B ubiquitination and activating ER‐phagy, AMFR alleviates progressive fibrosis and cardiac dysfunction by inhibiting the mTORC1 pathway. Consequently, these findings underscore the essential role of AMFR‐driven ER‐phagy in mitigating the progression of fibrotic responses, offering a potential therapeutic target for preventing heart ...
Zhixiang Wang, Kaifan Niu, Wei Liu, Xinyun Wang, Boshen Yang, Taixi Li, Yizhi Chen, Yuanyuan Jin, Yu Chen, Yangyi Lin, Xian Jin   +10 more
wiley   +1 more source

How drying methods and carrot varieties influence the acrylamide formation in carrot-enriched breads? [PDF]

Food Chem X
Swiacka J, Kaiser V, Bertsche U, Schwadorf K, Koenzen E, Jekle M.   +5 more
europepmc   +1 more source

Microwave‐Activated Bacterial Biorobot for Multimodal Cancer Therapy

Advanced Science, EarlyView.
An Escherichia coli bacterial biorobot is engineered for localized microwave activation in cancer therapy. Upon activation at tumor sites, the biorobot releases glucose oxidase, inducing tumor cell death via glucose depletion and H2O2 generation catalyzed by Cu2O.
Huilan Zhuang, Yongjian Zhang, Yajuan Fu, Dangjin Ke, Qi Chen, Sijie Shao, Panpan Xue, Yuanchun Chen, Xuemei Zeng, Shuangqian Yan   +9 more
wiley   +1 more source

A thin film optoelectronic photodetector of spherical and linear resonators via one-pot synthesis of Bi(III) oxide/polypyrrole nanocomposite. [PDF]

Sci Rep
Alkallas FH, Rabia M, Kusmartsev FV, Trabelsi ABG.   +3 more
europepmc   +1 more source

Mesenchymal Stromal Cells Play an Analgesic Role Through a Npy2r Sensory Neuron‐Mediated Lung‐to‐Brain Axis

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSC) are considered a promising alternative for neuropathic pain (NP) treatment, but underlying mechanisms remain elusive. Huang et al. illustrate that a Npy2r sensory neuron‐related lung–brain axis contributes to MSC analgesia.
Jing Huang, Taihe Zhou, Yueming Sun, Yuanchen Ma, Yiwen Deng, Keyu Chen, Ruijie Li, Yuan Qiu, Tao Wang, Xiaoyong Chen, Li Huang, Lu Zhu, Xueyi Tu, Ying Wang, Zheming Liu, Rouchen Lin, Yunli Tong, Yuantao Li, Heshe Li, Lin Nie, Rui Fang, Jianqi Feng, Xuhong Wei, Xia Feng, Andy Peng Xiang, Xiaoran Zhang   +25 more
wiley   +1 more source

Thermofluidic Nonequilibrium Assembly of Reconfigurable Functional Structures. [PDF]

ACS Nano
Quinn DJ, Paul D, Cichos F.
europepmc   +1 more source

Stiffness‐Tunable Neurotentacles for Minimally Invasive Implantation and Long‐Term Neural Activity Recordings

Advanced Science, EarlyView.
A hydraulically actuated “Neurotentacle” probe offers tunable stiffness for precise implantation into the deep brain without rigid shuttles or dissolvable coatings. It stiffens during insertion to penetrate tissue and softens afterward to minimize damage and enable stable long‐term recordings.
Yang Wang, Xing Xu, Xiaowei Yang, Rongyu Tang, Ying Chen, Shan Zang, Yijun Wang, Jing Liang, Weihua Pei   +8 more
wiley   +1 more source

Moderate heating renders 7.8-million-year-old sedimentary organic matter bioavailable. [PDF]

Sci Adv
Gan S, Heuer VB, Schmidt F, Wörmer L, Wang F, Adhikari RR, Hatcher P, Pearson A, Hinrichs KU.   +8 more
europepmc   +1 more source

BRD4 Signaling Maintains the Differentiated State of β Cells

Advanced Science, EarlyView.
The comprehensive exploration revealed the critical role of BRD4 in β cells. BRD4 plays a fundamental role in maintaining β cell differentiation because both long‐term and acute BRD4 deficiency result in a reduction in insulin secretion and downregulation of differentiation markers.
Fuqiang Liu, Guang Liu, Jia Song, Yujing Sun, Mengmeng Yang, Hualin Liu, Hongkai Zhao, Jiamu Chen, Qincheng Qiao, Siyue Li, Chenglong Yu, Jingru Qu, Ying Zou, Tixiao Wang, Jidong Liu, Lei Zhao, Huihui Tian, Tao Huang, Manna Zhang, Li Chen, Ruxing Zhao, Yuanyuan Du, Xinguo Hou   +22 more
wiley   +1 more source

Sex-Specific Behavioral Features of the Prenatal Valproic Acid Rat Model of Autism Spectrum Disorder. [PDF]

Brain Sci
Mamali PM, Dignon C, Ngwenya A, Maseko BC.   +3 more
europepmc   +1 more source