Results 181 to 190 of about 986,598 (243)

A20 Inhibits IFN‐γ Signaling in Hepatocellular Carcinoma Cells by Binding to STAT1, Compromising Anti‐Tumor Immunity

open access: yesCancer Science, EarlyView.
A20 suppresses IFN‐γ signaling in HCC cells by binding to STAT1 through its ZnF7 domain, thereby reducing CXCL9, CXCL10, and HLA‐ABC expression, ultimately impairing CD8+ T‐cell‐mediated anti‐tumor immunity. ABSTRACT Immune checkpoint blockade (ICB) has demonstrated efficacy in clinical cancer therapy; however, a significant proportion of cancer ...
Yanlei Dong   +14 more
wiley   +1 more source

Volumetric FLASH dosimetry<i>in vivo</i>using real-time radiacoustic imaging. [PDF]

open access: yesPhys Med Biol
Bjegovic K   +9 more
europepmc   +1 more source

Beauty in the Eye of AI: Aligning LLMs and Vision Models with Human Aesthetics in Network Visualization

open access: yesComputer Graphics Forum, EarlyView.
Abstract Network visualization has traditionally relied on heuristic metrics, such as stress, under the assumption that optimizing them leads to aesthetic and informative layouts. However, no single metric consistently produces the most effective results.
X. Li, P. Zhang, X. Wang, H. Shen, Y. Hu
wiley   +1 more source

Venlafaxine reduces hot flashes in hormone receptor-positive breast cancer patients receiving tamoxifen: a prospective single-arm, open-label trial. [PDF]

open access: yesBreast Cancer
Sato R   +13 more
europepmc   +1 more source
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Climacteric Hot Flash

Maturitas, 1981
No data are available on either quantitative or qualitative aspects of the climacteric hot flash, yet the phenomenon is widely treated despite unknown aetiology. A basic assumption of this study was that a more complete understanding and description of women with hot flashes would identify alternatives to oestrogens used by women for relief of the hot ...
Ann M. Voda
exaly   +3 more sources

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