Results 181 to 190 of about 67,868 (236)

Oral Astilbin Nanogels Modulate Senescence‐Associated CD4+ T Cells and Promote Treg Induction in Aged Mice with Colitis

open access: yesAdvanced Science, EarlyView.
Fluorinated β‐glucan/pectin nanogels enable colon‐targeted oral delivery of astilbin through gastrointestinal protection, β‐glucanase‐responsive release, mucus penetration, and prolonged retention. The released astilbin attenuates senescence‐associated features of CD4+ T cells and promotes Treg responses, while the nanogel matrix modulates the gut ...
Lei Zhao   +11 more
wiley   +1 more source

Multi‐Functional Smart Skin for High‐Efficiency Energy‐Saving Buildings

open access: yesAdvanced Science, EarlyView.
A scalable multifunctional smart skin (MSS) with broadband modulation, zero‐energy input controllable operation mode, and thermal insulation is designed by assembling thermal managing unit of high solar reflectance and low thermal conductivity and actuation unit of multi‐responsive shape‐memory effect.
Zongxu Na   +5 more
wiley   +1 more source

Mn/Zn Bimetallic MOF‐Integrated Hydrogel Alleviates Excessive Mitochondrial Fission in BMSCs to Promote Osteoporotic Jawbone Repair

open access: yesAdvanced Science, EarlyView.
Excessive reactive oxygen species (ROS) and chronic inflammation impair bone marrow‐derived mesenchymal stem cells (BMSCs), contributing to poor healing in osteoporotic jawbone defect. The gelatin methacryloyl hydrogel loaded with manganese‐doped zeolitic imidazolate framework (Mn‐ZIF‐8@GelMA) promotes regeneration through redox regulation and ...
Xiayue Jin   +6 more
wiley   +1 more source

A bibliometric analysis of global research trends in tumor microenvironment based nanotherapy. [PDF]

open access: yesDiscov Nano
Wu B   +8 more
europepmc   +1 more source

Atlas‐Guided CD55‐Enriched Neutrophil Extracellular Vesicles for Complement–Macrophage Modulation in Diabetic Wounds

open access: yesAdvanced Science, EarlyView.
ABSTRACT Diabetic wounds are characterized by persistent inflammation and impaired immune resolution, yet the therapeutic translation of single‐cell atlases into rational immunomodulatory strategies remains limited. Here, integration of diabetic‐wound single‐cell transcriptomic datasets identifies a neutrophil subpopulation enriched in cluster of ...
Tairong Cui   +12 more
wiley   +1 more source

Hypothalamic POMC Neurons Gate the Fear‐Feeding Trade‐Off

open access: yesAdvanced Science, EarlyView.
Hungry animals must continually arbitrate between feeding and defensive behaviors when confronted with potential threats. We show that hypothalamic POMC neurons engage CRH‐expressing stress circuits and downstream hormonal responses to coordinate this behavioral selection between competing behaviors.
Cristina Miralpeix   +16 more
wiley   +1 more source

Dramatic Enhancement and Integration of Properties in Pork Belly‐Inspired All‐Biomass Composite Films via Facile, Sustainable, and Controllable Design

open access: yesAdvanced Science, EarlyView.
A pork belly‐inspired all‐biomass composite film was constructed through layer‐by‐layer assembly of cellulose nanofibers (CNFs), gelatin, and graphitized carbon nanosheets (GCNs) via hydrogen bonding and π–π stacking interactions. The excellent mechanical properties, effective thermal management, and outstanding EMI shielding performance of the ...
Junchao Ren   +12 more
wiley   +1 more source

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