Results 61 to 70 of about 857,013 (301)

Effect of Mach number on the structure of turbulent spots [PDF]

, 2006
Direct numerical simulations have been performed to study the dynamics of isolated turbulent spots in compressible isothermal-wall boundary layers. Results of a bypass transition scenario at Mach 2, 4 and 6 are presented.
Krishnan, L., Sandham, N.D.
core   +1 more source

Focal areas of increased lipid concentration on the coating of microbubbles during short tone-burst ultrasound insonification. [PDF]

PLoS ONE, 2017
Acoustic behavior of lipid-coated microbubbles has been widely studied, which has led to several numerical microbubble dynamics models that incorporate lipid coating behavior, such as buckling and rupture.
Klazina Kooiman, Tom van Rooij, Bin Qin, Frits Mastik, Hendrik J Vos, Michel Versluis, Alexander L Klibanov, Nico de Jong, Flordeliza S Villanueva, Xucai Chen   +9 more
doaj   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Interpretation of Hot Spots in Wuhan New Town Development and Analysis of Influencing Factors Based on Spatio-Temporal Pattern Mining

ISPRS International Journal of Geo-Information
The construction of new towns is one of the main measures to evacuate urban populations and promote regional coordination and urban–rural integration in China.
Haijuan Zhao, Yan Long, Nina Wang, Shiqi Luo, Xi Liu, Tianyue Luo, Guoen Wang, Xuejun Liu   +7 more
doaj   +1 more source

Geochemistry and Distribution of Recycled Domains in the Mantle Inferred From Nd and Pb Isotopes in Oceanic Hot Spots: Implications for Storage in the Large Low Shear Wave Velocity Provinces

Geochemistry, Geophysics, Geosystems, 2018
Subduction of continental and oceanic crust is thought to give rise to geochemically distinct reservoirs in the mantle called EM (enriched mantle) and HIMU (high μ = 238U/204Pb), respectively.
M. G. Jackson, T. W. Becker, J. G. Konter   +2 more
doaj   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Gold Nanorod Assemblies: The Roles of Hot-Spot Positioning and Anisotropy in Plasmon Coupling and SERS

Nanomaterials, 2020
Plasmon-coupled colloidal nanoassemblies with carefully sculpted “hot-spots” and intense surface-enhanced Raman scattering (SERS) are in high demand as photostable and sensitive plasmonic nano-, bio-, and chemosensors. When maximizing SERS signals, it is
Priyanka Dey, Verena Baumann, Jessica Rodríguez-Fernández   +2 more
doaj   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Genome-wide mapping of hot spots of DNA double-strand breaks in human cells as a tool for epigenetic studies and cancer genomics

Genomics Data, 2015
Hot spots of DNA double-strand breaks (DSBs) are associated with coordinated expression of genes in chromosomal domains (Tchurikov et al., 2011 [1]; 2013).
N.A. Tchurikov, O.V. Kretova, D.M. Fedoseeva, V.R. Chechetkin, M.A. Gorbacheva, A.V. Snezhkina, I.R. Alembekov, G.I. Kravatskaya, Y.V. Kravatsky   +8 more
doaj   +1 more source