Results 91 to 100 of about 23,287,430 (320)

Multiwavelength study of Cygnus A III. Evidence for relic lobe plasma

, 2009
We study the particle energy distribution in the cocoon surrounding Cygnus A, using radio images between 151 MHz and 15 GHz and a 200 ks Chandra ACIS-I image.
Alexander, Baars, Belsole, Blundell, Blundell, Blundell, Carilli, Carilli, Carilli, Carilli, Churazov, Dennett-Thorpe, Dickey, Grevesse, Ian Heywood, Kaastra, Kaastra, Kassim, Katherine M. Blundell, Katrien C. Steenbrugge, Lazio, Leahy, Leahy, Longair, Markevitch, Owen, Perley, Rudnick, Rybicki, Scheuer, Scheuer, Schoenmakers, Shabala, Steenbrugge, Steenbrugge, Walker, Wilson   +36 more
core   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Identifying potential urban focal points using multiple centrality assessment (MCA): Da Nang’s center as a case study

Tạp chí Khoa học và Công nghệ
Conventionally, identifying urban focal points is primarily based on subjective and intuitive evaluations. This paper aims to establish an objective method for identifying urban focal points by applying Multiple Centrality Assessment (MCA), a spatial ...
Ngoc Hong Nguyen, Trung Xuan Nguyen
doaj   +1 more source

Optimal microscale water cooled heat sinks for targeted alleviation of hotspot in microprocessors [PDF]

, 2014
This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014), Poulikakos, D, Sharma, CS, Tiwari, MK   +3 more
core  

Quasi-periodic pulse amplitude modulation in the accreting millisecond pulsar IGR J00291+5934

, 2017
We introduce a new method for analysing the aperiodic variability of coherent pulsations in accreting millisecond X-ray pulsars. Our method involves applying a complex frequency correction to the time-domain light curve, allowing for the aperiodic ...
Bult, Peter, van der Klis, Michiel, van Doesburgh, Marieke   +2 more
core   +1 more source

The Abundance of X-Shaped Radio Sources I. VLA Survey of 52 Sources With Off-Axis Distortions [PDF]

, 2015
Cheung identified a sample of 100 candidate X-shaped radio galaxies using the NRAO FIRST survey; these are small-axial-ratio extended radio sources with off-axis emission.
Cohen, Jake P., Lu, Jing, Roberts, David H., Saripalli, Lakshmi, Subrahmanyan, Ravi   +4 more
core   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Do Protected Areas Improve Ecosystem Services? A Case Study of Hoh Xil Nature Reserve in Qinghai-Tibetan Plateau

Remote Sensing, 2020
Although there is a consensus that protected areas (PAs) can provide various ecosystem services, it is unclear whether protected areas effectively contribute to the preservation and enhancement of ecosystem services.
Jie Zeng, Tianyang Chen, Xiaowei Yao, Wanxu Chen   +3 more
doaj   +1 more source

Varying disc-magnetosphere coupling as the origin of pulse profile variability in SAX J1808.4-3658

, 2011
Accreting millisecond pulsars show significant variability of their pulse profiles, especially at low accretion rates. On the other hand, their X-ray spectra are remarkably similar with not much variability over the course of the outbursts. For the first
Alessandro Patruno, Altamirano, Arnaud, Askar Ibragimov, Balbus, Bildsten, Burderi, Burderi, Burderi, Cackett, Chakrabarty, Davis, Deloye, Fabian, Falanga, Frank, Fromang, Galloway, Galloway, Ghosh, Ghosh, Gierliński, Gierliński, Gierliński, Gilfanov, Godet, Hartman, Hartman, Hartman, Ibragimov, Ibragimov, in, Jahoda, Jari J. E. Kajava, Juri Poutanen, Kluźniak, Lamb, Long, Lovelace, Lovelace, Marja Annala, Markwardt, Markwardt, Matt, Matt, Mitsuda, Morrison, Ng, Papitto, Papitto, Papitto, Patruno, Patruno, Patruno, Patruno, Patruno, Patruno, Poutanen, Poutanen, Poutanen, Poutanen, Poutanen, Poutanen, Rappaport, Riggio, Riggio, Romanova, Romanova, Shakura, Shimura, Simon, Uzdensky, Uzdensky, Uzdensky, Viironen, Wang, Wang, Wijnands   +77 more
core   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source