Results 111 to 120 of about 23,287,430 (320)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Variability of Interpolation Errors and Mutual Enhancement of Different Interpolation Methods

Applied Sciences
Data interpolation methods are important statistical analysis tools that can fill in data gaps and missing areas by predicting and estimating unknown data points, thereby improving the accuracy and credibility of data analysis and research.
Yunxia He, Mingliang Luo, Hui Yang, Leichao Bai, Zhongsheng Chen   +4 more
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Multi-scenario territorial spatial simulation and dynamic changes: A case study of Jilin Province in China from 1985 to 2030

Open Geosciences
Territorial spatial resource changes play an irreplaceable role in the human development process, providing the necessary dependency conditions and ecosystem services for human production and life.
Shi Dan, Liu Xuan, Jin Jing, Wan Daiji, Chen Baolong, Liu Jiping   +5 more
doaj   +1 more source

Soft Handoff and Uplink Capacity in a Two-Tier CDMA System

, 2005
This paper examines the effect of soft handoff on the uplink user capacity of a CDMA system consisting of a single macrocell in which a single hotspot microcell is embedded. The users of these two base stations operate over the same frequency band.
Greenstein, Larry J., Kishore, Shalinee, Poor, H. Vincent, Schwartz, Stuart C.   +3 more
core   +1 more source

Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou, Carl D. Langefeld, Padmini Sekar, Mary Comeau, Timothy Howard, Tamara N. Kimball, Chen Bowang, Hyacinth I. Hyacinth, Jonathan Rosand, Christopher D. Anderson, Caspar Grond‐Ginsbach, Daniel Woo, Stacie L. Demel   +12 more
wiley   +1 more source

Socio-technical Security Analysis of Wireless Hotspots [PDF]

, 2014
We present a socio-technical analysis of security of Hotspot and Hotspot 2.0. The analysis focuses is user-centric, and aim at understanding which user action can compromise security in presence of a attacker. We identify research questions about possible factors that may affect user's security decisions, and propose experiments to answer them.
Ferreira, Ana, Huynen, Jean-Louis, Koenig, Vincent, Lenzini, Gabriele   +3 more
openaire   +2 more sources

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

Advanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice, Krzysztof S. Stopka, Michael D. Sangid   +2 more
wiley   +1 more source

Virusplot: a web server for viral integration analysis and visualization

Frontiers in Oncology
The integration of viral DNA into the human genome is a critical event in the pathogenesis of various cancers. This process leads to genomic instability, disrupts cellular regulatory mechanisms, and activates oncogenes or inactivates tumor suppressor ...
Erqiang Hu, Erqiang Hu, Erqiang Hu, Jianhong An, Jianhong An, Jianhong An, Adam J Gersten, Adam J Gersten, Nicole Wu, Nicole Kawachi, Jing Zhu, Gregory Rosenblatt, Stelby Augustine, Richard V. Smith, Jeffrey E Segall, Harry Ostrer, Antonio L Amelio, Antonio L Amelio, Christine H. Chung, Michael B. Prystowsky, Thomas J. Ow, Thomas J. Ow, Wenjun Deng, Shanye Yin, Shanye Yin, Shanye Yin   +25 more
doaj   +1 more source

Social Hotspot Analysis and Trade Policy Implications of the Use of Bioelectrochemical Systems for Resource Recovery from Wastewater

Sustainability, 2018
Bioelectrochemical systems (BESs) have been catalogued as a technological solution to three pressing global challenges: environmental pollution, resource scarcity, and freshwater scarcity.
Bolaji Shemfe, Siddharth Gadkari, J. Sadhukhan   +2 more
semanticscholar   +1 more source