Results 131 to 140 of about 790 (203)

Engineering Extracellular Vesicles: Strategies for Functional Modification and Clinical Translation

open access: yesiNew Medicine, EarlyView.
The engineering modification strategies of extracellular vesicles (EVs). This figure presents the four core technical systems for the engineering modification of EVs, including direct modification strategies (physical and chemical methods), biological engineering methods, and hybrid and bionic strategies.
Zhouming Cheng   +3 more
wiley   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

open access: yesInterdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li   +7 more
wiley   +1 more source

Prognostic Value of Combined FDG PET and MRI Analysis of Cervical Cancer: A Systematic Review and Meta‐Analysis

open access: yesJournal of Medical Radiation Sciences, EarlyView.
This systematic review and meta‐analysis synthesised FDG PET/MRWE biomarkers in cervical cancer, including a pooled analysis of the association between metabolic activity (SUV‐based metrics) and tumour diffusion characteristics (ADC measures). Prognostic evidence from the included studies was also analysed to identify PET‐ and MRI‐based parameters, as ...
William Wei   +2 more
wiley   +1 more source

Observed Linkages Between Marine Heatwaves and Extreme Weather Over Land: A New Zealand Case Study

open access: yesInternational Journal of Climatology, EarlyView.
Marine heatwaves consistently warm New Zealand's land surface, but rainfall impacts occur only when synoptic systems enable moisture transport. This 38‐year analysis shows MHWs act as thermodynamic background drivers of heat and conditional amplifiers of extreme rainfall events or droughts.
Matthew Chinappa   +3 more
wiley   +1 more source

Tracking Summer Greenland Blocking: The Upstream Pathway Shapes Historical Extremes and Future Change

open access: yesInternational Journal of Climatology, EarlyView.
This study investigates summer Greenland atmospheric blocking using the Lagrangian tracking Python package blocktrack applied to ERA5 reanalysis and CMIP6 models. Two types of blocks—upstream (Northern Canada origin) and retrograding (Northern Atlantic origin)—are distinguished, with upstream blocks driving recent observed frequency increasing trends ...
Michele Filippucci   +2 more
wiley   +1 more source

Climatic Drivers of the Area Burned by Winter Wildfires in Northern Italy

open access: yesInternational Journal of Climatology, EarlyView.
This study investigates winter wildfires occurring between November and April in northern Italy over the period 2008–2022. By integrating high‐resolution burned‐area data with gridded climatic indices derived from 150 weather stations, it identifies spatial and temporal wildfire patterns, highlights the most fire‐prone mountain areas through pixel ...
Alice Baronetti   +2 more
wiley   +1 more source

Frequent, Intense and Prolonged Human‐Perceived Heat Waves Over the Arabian Peninsula in Recent Decades

open access: yesInternational Journal of Climatology, EarlyView.
The spatial distribution of WBGT exhibits a widespread and significant warming trend across the Arabian Peninsula (AP), with, particularly, strong increases observed over the central and northern inland and eastern coastal regions of Saudi Arabia, Kuwait and Qatar, where trends exceed ~0.25°C decade−1.
Safi Ullah   +7 more
wiley   +1 more source

Multi‐Timescale Drought Evolution in Greece (1960–2022) From Station‐Based SPI and SPEI

open access: yesInternational Journal of Climatology, EarlyView.
Using homogenized data from 67 HNMS stations in Greece (1960–2022), we calculated SPI and SPEI at 1–12‐month scales to characterize meteorological to hydrological drought. We quantified the network‐based spatial extent of drought, compared SPI and SPEI drought signals, and tested changes with autocorrelation‐robust Mann–Kendall trends and Pettitt ...
Michael Samouris   +3 more
wiley   +1 more source

Intercomparison of a Regional Climate Model Ensemble for Selected European Catchments

open access: yesInternational Journal of Climatology, EarlyView.
This study analyzes a regional climate model ensemble for water cycle and water resource research with two models. Results show that ICON generally outperforms TSMP1 simulations, mainly with 2‐m temperature and precipitation. These findings serve as a baseline evaluation that shows how key structural differences influence the model skill.
Jane Leonor Roque   +10 more
wiley   +1 more source

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