Results 191 to 200 of about 44,235 (254)

PhosSight: A Unified Deep Learning Framework Boosting and Accelerating Phosphoproteome Identification to Enable Biological Discoveries

Advanced Science, EarlyView.
PhosSight is a unified deep‐learning framework for phosphoproteome identification, featured by a phosphorylation‐aware detectability predictor. It improves identification sensitivity in DDA through deep re‐localization and rescoring, accelerates DIA searches by detectability‐guided spectral library pruning, and expands phosphoproteome coverage to ...
Ben Wang, Zhiyuan Cheng, Chengying She, Hongwei Zhao, Jiahui Zhang, Lin Lv, Zhihao Yan, Hongwen Zhu, Lizhuang Liu, Yan Fu, Xinpei Yi   +10 more
wiley   +1 more source

Differential transcriptomic and metabolomic landscape between human hearts donated after cardiac vs brain death. [PDF]

J Heart Lung Transplant
Sicim H, Abou El Ela A, Lu S, Karunasumetta C, Danesh S, Knop G, Azzam FA, Gao W, Wang Y, Zhu W, Pagani FD, Lei I, Tang PC.   +12 more
europepmc   +1 more source

Single‐Cell Annotation and Localization via Integrating Spatial Transcriptomics Maps the Mouse Ocular Atlas and RAO Dynamics

Advanced Science, EarlyView.
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du, Yinming Li, Ziyue Li, Yuedan Wang, Shaopeng Li, Yijie Wang, Yingying Qu, Bingyang Lv, Ying Li, Ting Chen, Yu Zhou, Xuan Xiao   +11 more
wiley   +1 more source

Spontaneous Coronary Artery Dissection in Highly Active Individuals: Insights From a Prospective Registry. [PDF]

JACC Adv
Battenberg AE, Carey P, Larson KF, Hayes SN, Smith JR, Baker SE, Bonikowske AR, Tweet MS.   +7 more
europepmc   +1 more source

Imaging‐Guided Live Single‐Cell Lipid Profiling of Leader and Follower Cells During Collective Migration of Triple‐Negative Breast Cancer Cells

Advanced Science, EarlyView.
Integrated single‐cell mass spectrometry reveals distinct lipidomic signatures that differentiate leader and follower phenotypes in migratory breast cancer cells. Phenotype‐specific alterations across various lipid classes, including fatty acids and phosphatidylcholines, underpin functional heterogeneity.
Xiaoyue Huang, Judit González Riera, Mai Nguyen, Jeremy Broekhuis, Sylvia E. Le Dévédec, Ahmed Ali, Thomas Hankemeier   +6 more
wiley   +1 more source

Association Between Criminal Legal System Involvement and HIV Prevention and Care Among Transgender Women of Color: The TURNNT Cohort Study. [PDF]

LGBT Health
Furuya A, Whalen A, Radix A, Park SH, Contreras J, Scheinmann R, Herrera C, Watson K, Callander D, Brown KA, Schneider JA, Lim S, Trinh-Shevrin C, Duncan DT.   +13 more
europepmc   +1 more source

Pathway-specific canalization and plasticity of gene expression during <i>C</i>. <i>elegans</i> dauer development. [PDF]

iScience
Corchado JC, Selvarasu K, Prahlad V.
europepmc   +1 more source

Hanta on the Hondius - public health and bioethical perspectives of the recent <i>Andes</i> hantavirus cruise ship outbreak. [PDF]

New Microbes New Infect
Tsiodras S, Gkrania-Klotsas E, Mora-Rillo M, Gupta N, Drexler JF, Jokelainen P, Pellejero-Sagastizabal G, Barac A, Paño-Pardo JR, Lescure FX, Grobusch MP.   +10 more
europepmc   +1 more source

Induction and regulation of reversible suspended animation in C. elegans. [PDF]

Nat Commun
Liu J, Wang B, Leon Catrow J, Pearce Q, Ji Z, Yang SW, Balakrishnan A, Cox JE, Ma DK.   +8 more
europepmc   +1 more source