Results 241 to 250 of about 2,054,613 (335)

From on-call to on-site: the impact of 24-hour in-house neonatology on billing patterns and physician productivity. [PDF]

J Perinatol
Donohue L, Lakshminrusimha S.
europepmc   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

The LINK-Lombardia NeuroIntensive care Network. [PDF]

J Anesth Analg Crit Care
Guglielmi A, Graziano F, Vargiolu A, Amigoni M, Berselli A, Cabrini L, Chieregato A, Dell'Acqua A, Dell'Avanzo G, Fassini P, Galassini E, Gemma M, Grappa E, Gritti P, Iaquaniello C, Mangili P, Mazza GM, Mistraletti G, Muttini S, Nguyen M, Ortolano F, Pagani M, Panzeri C, Piva S, Pressato LS, Rasulo F, Sangalli F, Villa F, Viscone A, Zerbi SM, Zoerle T, Citerio G.   +31 more
europepmc   +1 more source

ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells

Advanced Science, EarlyView.
With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao, Shannon Erhardt, Li Tang, Xiaotong Chen, Stephen M Farmer, Zixiu Cheng, Wen Chen, Ella Ziyuan Lu, Kihan Sung, Chang‐Ru Tsai, Mingjie Zheng, Sheng Zhang, Yang Liu, Jianxin Wang, Min Li, James F Martin, Jun Wang   +16 more
wiley   +1 more source

Immunogenicity Publication Bias and Its Consequences for Predictive Models: A Call for Transparent Reporting. [PDF]

CPT Pharmacometrics Syst Pharmacol
Tascedda S, Hu Z, Grimm HP, Franssen LC.
europepmc   +1 more source

Idiosyncratic long call-like vocalisations in two zoo-housed Bornean orang-utan females [PDF]

Tom S. Roth, Clemens von Wulffen, Megan Fox, James Askew, Michelle Spierings, Juan Olvido Perea‐García   +5 more
openalex   +1 more source

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
wiley   +1 more source

Retraction: Optimization of house price evaluation model based on multi-source geographic big data and deep neural network. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source