Results 81 to 90 of about 1,354,963 (295)
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
The Hospital at Home Model: Bringing Hospital-Level Care to the Patient [PDF]
, 2016 Presbyterian's Hospital at Home program, launched in 2008, is based on a model developed in the mid-1990s by Bruce Leff, M.D., a geriatrician and health services researcher at Johns Hopkins University, who noticed that many of his patients suffered poor ...
Douglas McCarthy +2 more
core
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
Public Health ResearchThis report summarises the research, as commissioned and as undertaken, and lessons learnt in the ‘Do Safe and Well Visits delivered by the Fire and Rescue Service reduce falls and improve quality of life among older people’ randomised controlled trial ...
Sarah Cockayne +15 more
doaj +1 more source
Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley +1 more source
Communicating towards justice in ‘The Subaltern Voice’ (TSV) [PDF]
, 2009 We write with a voice of the marginalised in mind, as both marginalised women scholars writing from a critical perspective on human organisation and as privileged human beings with concern for those more dangerously excluded from The Master’s House.
Humphries, Maria, McNicholas, Patty
core +1 more source
Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann +17 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyrophosphate (CPP) crystal arthritis. Methods We conducted a post hoc analysis of the COLCHICORT trial, which compared colchicine and prednisone for the treatment of acute CPP crystal arthritis, using a ...
Tristan Pascart +14 more
wiley +1 more source
Innovative educational approaches to house calls in the time of COVID-19. [PDF]
J Am Geriatr Soc, 2021 Robertson ML +3 more
europepmc +1 more source
Love is in the Airwaves: Contesting Mass Incarceration with Prisoners\u27 Radio [PDF]
, 2018 Building on bell hooks’ conceptualization of love as a mode of political resistance, this article explores how prisoners’ radio employs love to combat injustice.
Benson, Eleanor R.
core +1 more source