Results 111 to 120 of about 166,356,720 (268)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ±
Sarah J. Wright +10 more
wiley +1 more source
Presidential threshold policy in Indonesian presidential election of 2019
Studia Humanitatis, 2018 In 2019 Indonesia would conduct simultaneous elections to elect legislative and executive members; members of House of Representatives, Regional Representatives Council, President and Vice President.
Azis Setyagama
doaj
Jurnal Hukum VolkgeistThe supervisory function of Commission III of the House of Representatives on law enforcement agencies is part of the checks and balances mechanism in the Indonesian constitutional system.
La Ode Muhamad Hiwayad
doaj +1 more source
The rise of partisanship and super-cooperators in the U.S. House of Representatives. [PDF]
PLoS One, 2015 Andris C +5 more
europepmc +1 more source