Results 111 to 120 of about 1,213,758 (309)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
HeliyonDandruff is a common and persistent scalp condition involving symptoms such as skin flaking, itching, and redness. This preliminary study aimed to investigate the biophysical and physiological characteristics of dandruff to develop preventive strategies.
Jaeyoon Kim +6 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Recommendation Card, Tampa School of Household Arts, circa 1915
, 1915 Sample recommendation card for entry into the Tampa School of Household Arts.https://digitalcommons.usf.edu/armwood_records/1011/thumbnail ...
Tampa School of Household Arts
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Noncooperative household consumption with caring [PDF]
We present a household consumption model that accounts for caring household members, while allowing for noncooperative behavior in decisions on public goods.
Bram DE ROCK +2 more
core +2 more sources
Enrollment Certificate, Tampa School of Household Arts, circa 1915
, 1915 Sample enrollment certificate for students at the Tampa School of Household Arts.https://digitalcommons.usf.edu/armwood_records/1010/thumbnail ...
Tampa School of Household Arts
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Netherlands Yearbook for History of Art / Nederlands Kunsthistorisch Jaarboek OnlineAbstract This essay is about the discovery of Maria van Van Nesse’s ledger, which was hidden in a Belgian family archive. With 123 mentions of paintings and drawings, listed among over 3,500 household expenses, Van Nesse instantly became the best documented art buyer of the seventeenth-century Republic, regardless of gender.
openaire +1 more source