Results 251 to 260 of about 3,219,282 (342)

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Adverse childhood experiences, basic psychological needs, and adolescent affective distress: Revisiting the buffering role of resilience factors. [PDF]

J Res Adolesc
Zhou K, Zhu X, Lu C, Yang Y, Chen S.
europepmc   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Household exposure, demographic and health characteristics associated with SARS-CoV-2 infection in a cohort study in Northern France. [PDF]

Sci Rep
Galmiche S, Pinaud L, Tondeur L, Pelleau S, Attia M, Castelain S, Staropoli I, Duru C, Koffi AD, Fernandes-Pellerin S, Jolly N, Roux E, Schwartz O, van der Werf S, White M, Fontanet A.   +15 more
europepmc   +1 more source

Spatioethnic Household Carbon Footprints in China and the Equity Implications of Climate Mitigation Policy: A Machine Learning Approach

Anthony Howell
openalex   +2 more sources

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Circulation of Salmonella spp. between humans, animals and the environment in animal-owning households in Malawi. [PDF]

Nat Commun
Wilson CN, Musicha P, Beale MA, Diness Y, Kanjerwa O, Salifu C, Katuah Z, Duncan P, Nyangu J, Mungu A, Deleza M, Banda L, Makhaza L, Elviss N, Jewell CP, Pinchbeck G, Feasey NA, Fèvre EM, Thomson NR.   +18 more
europepmc   +1 more source

Experimental Investigation of the Source of Acoustic Bursts Produced by Household Refrigerators

, 2001
S.M. McLevige, N.R. Miller
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Exploring outcomes between single and dual caregiver households participating in a parenting and family strengthening intervention in Rwanda: the case of Sugira Muryango. [PDF]

BMC Public Health
Ukwishaka J, Sezibera V, Pineros-Leano M, Betancourt TS.   +3 more
europepmc   +1 more source