Results 131 to 140 of about 557,653 (268)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Socio-Demographic and Household Environmental Conditions Associated With Prevalence of Diarrheal Disease in Burao, Somaliland. [PDF]

Environ Health Insights
Yosef DK, Hassan MA.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Psychological Issues, Prevalence and Predictors in Senegal: Evidence from the Senegal Demographic and Health Survey (DHS) 2023. [PDF]

Indian J Psychol Med
Tikhute VR, Reddy S, Fatokun BS, Devkate KD, Gawai P.   +4 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Improving Household Food Security Among Foreign-Born Residents of New York City Through Grocery Store Vouchers: A Pilot Program. [PDF]

J Public Health Manag Pract
Nieves CI, Nieves CI, Wohlman A, Arbelaez SA, Zamula A, Bonah N, Padilla CM, Narvaez L, Cuevas A, John P.   +9 more
europepmc   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Substance use and mental health outcomes in children and adolescents exposed to household dysfunction: mediating role of emotional intelligence. [PDF]

BJPsych Open
Ramírez M, San Martín N, Marques-Feixa L, Romero S, Monteserín-García JL, Mas A, Rapado-Castro M, Marín-Vila M, Blasco-Fontecilla H, Muñoz MJ, González-Pinto A, Zorrilla I, Fañanás L.   +12 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Determinants of Productivity and Sustainability in Small-Scale Dairy Industries: Evidence From the Salale Zone of Oromia, Ethiopia. [PDF]

Vet Med Sci
Geleta GM.
europepmc   +1 more source