Results 101 to 110 of about 1,166,912 (303)

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Molecular identification and genetic variation of urban tree-associated populations of Coptotermes gestroi (Blattodea: Rhinotermitidae) on Penang Island, Malaysia

Journal of Basic and Applied Zoology
Background Coptotermes gestroi is one of the most destructive subterranean termite species in Southeast Asia, causing structural damage in urban areas such as Penang Island, Malaysia.
Li Lim, Abdul Hafiz Ab Majid
doaj   +1 more source

Household Production and the Household Economy. [PDF]

Household production is the production of the goods and services by the members of a household, for their own consumption, using their own capital and their own unpaid labor.
Ironmonger, D.
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Dihydroavenanthramide D Enhances Skin Barrier Function through Upregulation of Epidermal Tight Junction Expression

Current Issues in Molecular Biology
Skin barrier dysfunction and thin epidermis are hallmarks of sensitive skin and contribute to premature aging. Avenanthramides are the primary bioactive components of colloidal oatmeal, a commonly used treatment to enhance skin barrier function.
Jiye Park, Jae Young Shin, Daehyun Kim, Seung-Hyun Jun, Eui Taek Jeong, Nae-Gyu Kang   +5 more
doaj   +1 more source

Household saving [PDF]

Household decisions on whether to save or spend play a key role in the outlook for aggregate demand. A range of factors could help to explain the fall in the household saving ratio over the period 1995 to 2007.
Berry, Stuart, Williams, Richard, Waldron, Matthew   +2 more
core  

Noncooperative household consumption with caring [PDF]

We present a household consumption model that accounts for caring household members, while allowing for noncooperative behavior in decisions on public goods.
Bram DE ROCK, Laurens CHERCHYE, Thomas DEMUYNCK   +2 more
core   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Biophysical characteristics of mild-dandruff scalp in association with hyperkeratinized corneocytes and the inflammatory cytokine interleukin-8: a preliminary study

Heliyon
Dandruff is a common and persistent scalp condition involving symptoms such as skin flaking, itching, and redness. This preliminary study aimed to investigate the biophysical and physiological characteristics of dandruff to develop preventive strategies.
Jaeyoon Kim, Yun-ho Choi, Jae young Shin, Jang Ho Joo, Heena Rim, Seung-Hyun Jun, Nae-Gyu Kang   +6 more
doaj   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source