Results 71 to 80 of about 3,485,548 (325)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Urbanization and humidity shape the intensity of influenza epidemics in U.S. cities
Science, 2018 Seasonal flu by ZIP code Influenza virus strikes communities in northern latitudes during winter, straining health care provision almost to the breaking point.
B. Dalziel +7 more
semanticscholar +1 more source
Acta Theologica, 2014 In a world characterized by power abuse and violence, where and how would people with the life-affirming ethos of God’s alternative kingdom be formed?
E. Mouton
doaj +1 more source
Family tree database of the National Health Information Database in Korea [PDF]
Epidemiology and Health, 2019 We constructed the family tree database (DB) by using a new family code system that can logically express interpersonal family relationships and by comparing and complementing health insurance eligibility data and resident register data of the National ...
Yeon-Yong Kim +3 more
doaj +1 more source
Rates and predictors of recurrent work disability due to common mental health disorders in the United States. [PDF]
, 2018 ContextDespite the high prevalence of work disability due to common mental disorders (CMD), no information exists on the rates and predictors of recurrence in a United States population.ObjectiveTo estimate recurrent work disability statistics and ...
Dewa, Carolyn S +2 more
core +3 more sources
Predictors for Nonaccidental Trauma in a Child With a Fracture-A National Inpatient Database Study. [PDF]
, 2020 BackgroundDespite heightened awareness and multidisciplinary efforts, a predictive model to help the clinician quantify the likelihood of nonaccidental trauma (NAT) in a child presenting with a fracture does not exist.
Sabharwal, Sanjeev +3 more
core +2 more sources
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
BMJ Open, 2019 Objectives To study the association of place-based socioeconomic factors with disease distribution by comparing hospitalisation rates in California in 2001 and 2011 by zip code median household income.Design Serial cross-sectional study testing the ...
Eva Raphael, R Gaynes
doaj +1 more source
Of impacts, agents, and functions: An interdisciplinary meta-review of smart home energy management systems research [PDF]
, 2020 Smart home energy management technologies (SHEMS) have long been viewed as a promising opportunity to manage the way households use energy. Research on this topic has emerged across a variety of disciplines, focusing on different pieces of the SHEMS ...
McIlvennie, C +2 more
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source