Results 241 to 250 of about 414,008 (316)

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Sexual and reproductive health service use of unmarried adolescents in Morogoro, Tanzania: insights from a cross-sectional household survey. [PDF]

Front Reprod Health
Morris BM, Chombo S, Ulrich CM, Kakoko DCV.   +3 more
europepmc   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Incidence, Impact, and Healthcare-Seeking Behavior for Extremity Fractures in Resource-Limited Settings: A Household Survey in Rural Tanzania. [PDF]

World J Surg
Binnerts JJ, Hendriks TCC, Okoth J, Gill-Wiehl A, Ranganathan K, Ehsan AN, Harun NW, Ogoya S, Bempong-Ahun N, Ibbotson G, Harrison WJ, Martin C, Edwards MJR, Hermans E, Chirangi BM.   +14 more
europepmc   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Community-Based Household Survey Among Children Aged 5-18 to Identify Disability Burden and Health-Related Quality of Life Following Road Traffic Accidents in Ujjain, India. [PDF]

Cureus
Pathak A, Baghel D, Jat J.
europepmc   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Use of tobacco and nicotine products among adolescents in Sub-Saharan Africa: protocol for a population-based multi-country household survey. [PDF]

Front Public Health
Kisia L, Mohamed SF, Kyule G, Tchoupé C, Abolarin O, Pokothoane R, Gelibo T, Iddi S, Okumu B, Mbaya N, Kadengye DT, Mirindi DM, Akiode A, Ademola T, Okezie U, Mdege ND.   +15 more
europepmc   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

SARS-CoV-2 seroprevalence and COVID-19 vaccination coverage in two states of Nigeria from a population based household survey. [PDF]

Sci Rep
Enyereibe NW, Ilori E, Steinhardt L, Stafford K, Dan-Nwafor C, Ochu CL, Ibrahim D, Alagi M, Ibrahim BS, Iwara IE, Mba N, Ibrahim Z, Ahmed RA, Botson I, Ogbonna SU, Igumbor E, Abubakar J, Ahmed N, Nwiyi GO, Ihemeje CE, Okoi C, John D, Ashikeni M, Muhammad BL, Iriemenam NC, Okunoye O, Greby SM, Bassey O, Okoye M, Blanco N, Mitchell A, Ipadeola O, Antonza GS, Mpamugo A, Makava F, Charurat M, Adebajo S, Swaminathan M, Ifedayo A, Ihekweazu C.   +39 more
europepmc   +1 more source