Results 111 to 120 of about 513,820 (315)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Which households use consumer credit in Europe? [PDF]
Which households use consumer credit? This paper addresses the question using harmonized data from Eurostat’s EU-SILC survey for nine European countries in the period 2005-08.
Cristiana Rampazzi +2 more
core
Health and Segregation: Iberian Jewish Responses to the Crisis of the Late Fifteenth Century
Cromohs: Cyber Review of Modern HistoriographyIn 1480, the Cortes of Toledo decreed the apartamiento (removal) of Jews from their quarters in urban areas, allowing a two-year period for its implementation.
Carmen Caballero Navas +1 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Households’ response to economic crisis [PDF]
This paper studies the economic impact of the current global economic downturn on the household sector. Household budgets can be negatively affected by declines in nominal wages and increases in unemployment. We empirically test this effect for the small
Jakubik, Petr
core
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Team approach promotes households to save energy at home
The energy saving issues becomes more important in order to achieve the EU energy efficiency target by 2020. Within the household sector lies one of the greatest energy saving potential [1].
Ozoliņa, Līga, Pelšs, Mārtiņš
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Food Spending in American Households, 2003-04
Average yearly expenditures on food in U.S. urban households increased between 2003 and 2004. Over the period, annual per capita spending on food rose from $2,035 to $2,207.
Blisard, Noel, Stewart, Hayden
core
The financial position of British households: evidence from the 2009 NMG survey [PDF]
The severe recession of the past year might be expected to have put the financial position of British households under considerable strain. Unemployment has risen significantly, credit conditions have tightened and many homeowners have seen their housing
Williams, Richard +3 more
core