Results 181 to 190 of about 261,498 (268)

Management, socioeconomics, and One Health determinants of tick infestation in communal cattle production systems of South Africa. [PDF]

Front Vet Sci
Sedina MP, Njoga EO, Oguttu JW.
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Cognitive-psychological mechanisms and decision-making in later life: the role of wealth perception capability. [PDF]

Front Psychol
He X, Zeng X, Jiang T.
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Prevalence of undernutrition and associated factors among children aged 6-59 months in rural model households in the Central Zone of Sidama regional state, Ethiopia: a community-based cross-sectional study using robust Poisson regression analysis. [PDF]

BMJ Open
Gujo AA, Amare HH, Estifanos MB, Aregu MB.   +3 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Assessing SARS-CoV-2 transmission in African households from the reanalysis of serosurveys. [PDF]

Am J Epidemiol
Cristancho-Fajardo L, Nkuba-Ndaye A, Simons E, Hozé N, Guichet E, Izia YA, Ndongo FA, Mbala-Kingebeni P, Soumah AA, Muzinga J, Tshiminyi-Munkamba P, Diallo MSK, Bissek AZ, Makiala-Mandanda S, Toure A, Ahuka-Mundeke S, Ayouba A, Etard JF, Peeters M, Roche B, Nikolay B, Delaporte E, Cauchemez S.   +22 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source