Results 41 to 50 of about 166,052 (288)
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Pattern of consumption budget allocation by the poor families
Journal of Economics, Business & Accountancy Ventura, 2015 Various allegations towards the poverty problems are due to the issue of cultural, consumption behavior, social dynamics, and policy support. This study deals with the pattern of communities spending behavior through modeling the allocation of house-hold
Rizal Edy Halim +2 more
doaj +1 more source
An Analysis of Single-person Households' Expenditure Pattern
Journal of the Korea Academia-Industrial cooperation Society, 2015 본 연구에서는 토빗모형을 이용하여 1인가구의 소비패턴이 연령별, 소득별로 얼마나 다른지 추정하였다. 분석을 위해 2006년부터 2012년까지 통계청 가계동향조사의 지출 데이터를 이용하였다. 추정결과, 음식료품, 주거 및 수도광열, 통신 지출을 제외한 모든 품목에서 1인가구의 소득탄력성은 1보다 크게 나타났으며 품목별로 다른 소비 특성을 보인다는 것을 확인했다. 또한 1인가구의 품목별 소득탄력성은 연령별, 소득별로 크게 차이를 보였다. 향후 1인가구의 관련 정책 또는 기업의 전략을 수립할 때 연령별, 소득별로 차별화된 접근이 필요할 것이다.
Moon-Soo Park +3 more
openaire +2 more sources
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Tobacco Induced Diseases, 2020 Introduction There is a growing literature on the ‘crowding-out’ effects of tobacco expenditure, particularly in Low-to-Middle Income Countries (LMICs).
Abdul Gafar A. Masa-ud +2 more
doaj +1 more source
FOOD DEMAND PATTERNS IN GHANAIAN URBAN HOUSEHOLDS [PDF]
Review of Agricultural and Applied Economics, 2018 This paper analysed food consumption patterns in Ghanaian urban households by comparing food commodity budget shares and estimating price and expenditure elasticities for eleven food commodity groups across different income groups.
Bernard SAKYIAMAH +1 more
doaj +1 more source
Aging and Cancer, EarlyView.Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source