Results 151 to 160 of about 4,048,714 (320)

PRECARIZED AGEING‐IN‐PERIFERIA: Low‐Income Older Adults in a Transforming Neighbourhood

International Journal of Urban and Regional Research, EarlyView.
Abstract In this article we investigate how intersecting forms of precarity shape the everyday practices of ageing‐in‐place developed by low‐income older adults in Via Milano, a historically segregated yet rapidly transforming neighbourhood in Brescia, northern Italy. We draw on qualitative and ethnographic research to examine how diverse urban changes—
Marco Alioni, Barbara Badiani
wiley   +1 more source

DNA‐Methylation for Risk‐Stratification of Women Without a Fully Visible Transformation Zone at Colposcopy: A Cross‐Sectional Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To evaluate the performance of DNA methylation markers for the detection of cervical precancer among screening‐positive older women without a fully visible transformation zone at colposcopy (TZ3). Design Cross‐sectional study. Setting Colposcopy clinics, Central Denmark Region, 2019–2021.
Karen Omann Binderup, Joachim Boers, Line Winther Gustafson, Berit Andersen, Lone Kjeld Petersen, Pinar Bor, Joost Gribnau, Wim G. V. Quint, Henk Van Den Munckhof, Mette Tranberg, Anne Hammer   +10 more
wiley   +1 more source

Relationships of Cognitive Function With Subsequent Device‐Measured Physical Activity and Sedentary Time in Healthy Individuals and Those With Bipolar Disorder: Findings From the UK Biobank

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background In bipolar disorder (BD), physical inactivity and sedentary behaviour are prevalent and have been linked to BD's cognitive symptoms, although the directionality of these links is not clear. This proof‐of‐concept study examined whether cognitive function during mid‐ and later‐life was prospectively related to physical activity and ...
Elysha Ringin, David W. Dunstan, Denny Meyer, Roger S. McIntyre, Neville Owen, Michael Berk, Susan L. Rossell, Mats Hallgren, Tamsyn E. Van Rheenen   +8 more
wiley   +1 more source

Endocannabinoid system gene expression in mesocorticolimbic brain regions of individuals with alcohol use disorder: A descriptive study

Addiction, EarlyView.
Abstract Aims To describe differences in the expression of genes encoding cannabinoid receptors (CNR1, CNR2), the associated receptor GRP55 and the enzymes fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MGLL) between individuals with alcohol use disorder (AUD) and controls in key mesocorticolimbic brain regions.
María Salud García‐Gutiérrez, Abraham Bailén Torregrosa, Francisco Navarrete, Auxiliadora Aracil‐Fernández, Gabriel Rubio, Jorge Manzanares   +5 more
wiley   +1 more source

Hospital waste Management —- Tackling Trash as a Team.

Pakistan Journal of Medicine and Dentistry
Clinical waste is a major source of infection amongst patients, hospital workers and the community. The Hospital Waste Management committee established in Dr.
Sana Ansari, Umme Habiba, Farzana Aslam, Arif Hussain   +3 more
doaj  

Club Cells in Nasal Epithelial Repair: Insights From an IL‐13‐Induced Inflammatory Model

Allergy, EarlyView.
Four inflammatory endotypes of CRSwNP, defined by eosinophil and neutrophil infiltration, show distinct patterns of basal, club, ciliated, and goblet cell expression in nasal epithelium. Using an ALI‐HNECs model, we demonstrate that IL‐13 impairs mucociliary function by promoting club‐to‐goblet cell differentiation while inhibiting club‐to‐ciliated ...
Zhi‐Qun Huang, Jing Liu, Jing Ye, Li‐Ying Sun, Hsiao Hui Ong, Yang Peng, Bing‐Qi Lin, Jun‐Hao Tu, Ke‐Shuang Wang, Yi‐Shan Xiong, Qing Luo, Mark Thong, Yu Xu, De‐Yun Wang   +13 more
wiley   +1 more source

A study on biomedical waste management in the healthcare sector. A pathway towards sustainability

Social Medicine
The present write-up deals with the determination of the awareness amongst the healthcare work force in a hospital setting – the awareness with regard to the biomedical waste management policy and practices.
Ammna Rakshanda, Vahid, Saad Bin Azhar
doaj  

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

Aerobic Exercise Ameliorates Adverse Vascular Remodeling in Diabetes via PDK1/FoxO1 Axis. [PDF]

FASEB J
Xie X, Zhang Z, Yang X, Chu M.
europepmc   +1 more source

BRD9 inhibition as potential treatment option for testicular germ cell tumors

Andrology, EarlyView.
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen, Christine Sanders, Florian Fronhoffs, Kai Funke, Glen Kristiansen, Hubert Schorle   +5 more
wiley   +1 more source