Results 191 to 200 of about 4,048,714 (320)

Effect of Delgocitinib Cream on Health‐Related Quality of Life in Patients With Moderate to Severe Chronic Hand Eczema

open access: yesContact Dermatitis, EarlyView.
Patient‐reported outcomes are an important complement to physician‐assessed clinical outcome measures in Chronic Hand Eczema. In a pooled analysis of two randomised, controlled trials, twice‐daily treatment with delgocitinib cream 20 mg/g significantly improved the health‐related quality of life of patients with moderate to severe Chronic Hand Eczema ...
Andrea Bauer   +7 more
wiley   +1 more source

Combining degree centrality and betweenness centrality of molecular networks can effectively pinpoint individuals at high risk of HIV transmission within the network. [PDF]

open access: yesFront Cell Infect Microbiol
Gan W   +13 more
europepmc   +1 more source

Impact of Allergic Contact Dermatitis on Health‐Related Quality of Life: A Cross‐Sectional Case–Control Study in a Spanish Population

open access: yesContact Dermatitis, EarlyView.
Allergic contact dermatitis markedly impairs quality of life (QoL) across symptoms, functioning and emotional domains. Using DLQI, Skindex‐29 and EQ‐5D‐5L, our study demonstrates a substantial multidimensional burden and highlights the need for routine, patient‐centred QoL assessment in clinical management.
Francisco José Navarro‐Triviño   +3 more
wiley   +1 more source

Mechanical Force Promotes Mitochondrial Transfer From Macrophages to BMSCs to Enhance Bone Formation

open access: yesCell Proliferation, EarlyView.
Mechanical tension activates Drp1‐mediated mitochondrial fission in macrophages, facilitating the release of Mito‐EVs that are subsequently transferred to BMSCs. Additionally, the CD200R‐CD200 interaction enhances the uptake of these mechanically stimulated macrophage‐derived Mito‐EVs by BMSCs, ultimately promoting osteogenic differentiation.
Yingyi Li   +8 more
wiley   +1 more source

Evaluation of Streptococcus mutans strains possessing genes encoding collagen-binding proteins in the Japanese population. [PDF]

open access: yesBMC Oral Health
Okuda M   +7 more
europepmc   +1 more source

Decoding the Role of Caveolin‐1 in Morphological Diversity and Self‐Renewal of Breast Cancer Cells

open access: yesCell Proliferation, EarlyView.
The silence of caveolin‐1 (Cav‐1) reproduced the morphological evolutionary behaviour of cancer cells, which is similar to the epithelial‐mesenchymal transition process. And Cav‐1 dependent morphological changes could affect cancer cell self‐renewal capacity through maintaining the morphological stability.
Shun Li   +14 more
wiley   +1 more source

NSUN2 mediates intestinal stem cell expansion and colorectal tumour initiation via MAPK/ERK signalling. [PDF]

open access: yesCell Death Dis
Bastem Akan A   +12 more
europepmc   +1 more source

Nanosilicates Enhanced Periodontal Angiogenesis by Regulating Microtubule Dynamic‐Mediated STAT3 Pathway

open access: yesCell Proliferation, EarlyView.
Nanosilicates triggered MAP4‐dependent microtubule remodelling via the ROS/MAPK pathway, shifting microtubules into a dynamic active state, which subsequently promoted activation of the STAT3 pathway, ultimately facilitating periodontal angiogenesis.
Lingling Shang, Yuhan Hu, Shaohua Ge
wiley   +1 more source

Draft genome sequences of two multidrug-resistant <i>Proteus mirabilis</i> isolates from hospital wastewater and a discharge point into Manila Bay, Philippines. [PDF]

open access: yesMicrobiol Resour Announc
Padon SDM   +8 more
europepmc   +1 more source

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