Results 181 to 190 of about 471,680 (266)

Programmable RNA N6,2´‐O‐Dimethyladenosine Editing

Advanced Science, EarlyView.
ABSTRACT N6,2’‐O‐dimethyladenosine (m6Am) is a prevalent RNA modification located at the first transcribed nucleotide adjacent to the 5′ cap of mRNAs, where it has been implicated in gene regulation. However, the lack of methods for precise, transcript‐specific manipulation of m6Am has limited its functional dissection.
Yang Li, Xiangmin Tan, Yaran Liu, Yongquan He, Bo Yuan, Ping Wang, Guangzhi Ma, Mengzhe Guo, Jian Zhou, Qiang Sun   +9 more
wiley   +1 more source

Identification and Validation of Tissue-Specific Housekeeping Markers for the Amazon River Prawn Macrobrachium amazonicum (Heller, 1862). [PDF]

Genes (Basel)
Lima GM, Rodrigues MAL, Paixão RV, Lutz Í, Aviz MAB, Sousa JDSADL, Maciel BR, Queiroz LD, Maciel CMT, Sampaio I, Varela ES, Maciel CR.   +11 more
europepmc   +1 more source

Smart Flexible Tactile Sensors: Recent Progress in Device Designs, Intelligent Algorithms, and Multidisciplinary Applications

Advanced Intelligent Discovery, EarlyView.
Flexible tactile sensors have considerable potential for broad application in healthcare monitoring, human–machine interfaces, and bioinspired robotics. This review explores recent progress in device design, performance optimization, and intelligent applications. It highlights how AI algorithms enhance environmental adaptability and perception accuracy
Siyuan Wang, Ming Dong, Rongrong Bao, Caofeng Pan   +3 more
wiley   +1 more source

Characterization of Pseudomonas mediterranea and Pseudomonas viridiflava strains associated with tomato pith necrosis in the Al Taif region, Saudi Arabia. [PDF]

Sci Rep
Ibrahim YE, Widyawan A, Al Masrahi AA, Al Hashel AF, Al Saleh MA.   +4 more
europepmc   +1 more source

gnSPADE: Incorporating Gene Network Structures Enhances Reference‐Free Deconvolution in Spatial Transcriptomics

Advanced Intelligent Systems, EarlyView.
gnSPADE integrates gene‐network structures into a probabilistic topic modeling framework to achieve reference‐free cell‐type deconvolution in spatial transcriptomics. By embedding gene connectivity within the generative process, gnSPADE enhances biological interpretability and accuracy across simulated and real datasets, revealing spatial organization ...
Aoqi Xie, Yuehua Cui
wiley   +1 more source

Phylogenetic identification of <i>Aeromonas crassostreae</i> from spinach, first isolate since species description. [PDF]

New Microbes New Infect
Martínez-Murcia A, García-Sirera A.
europepmc   +1 more source

‘I Don't Babysit’: Stay‐at‐Home Dads' Perspectives and Experiences Within Australian Society

Australian Journal of Social Issues, EarlyView.
ABSTRACT Stay‐at‐home‐dads are an emerging group in Australia, impacted by societal assumptions and expectations. However, there is a scarcity of research on the perspectives and experiences of fathers assuming stay‐at‐home dad roles within Australian society.
Elyse Manie, Patricia Taylor, Hayley McKenzie, Norma Barrett   +3 more
wiley   +1 more source

Reference Gene Validation for Quantitative PCR Analysis in 2D and 3D AML12 Hepatocyte Models. [PDF]

Biomedicines
Ivanova Z, Petrova V, Todorova B, Penev T, Grigorova N.   +4 more
europepmc   +1 more source

Mucin Glycoprotein Nanoparticles Enable a Selective Antisense Therapy for Oncogenic MicroRNAs

Advanced NanoBiomed Research, EarlyView.
Mucin glycoproteins are turned into nanoparticles by employing synthetic DNA strands, which have a dual function: they stabilize the nanoparticles and act as binding sites for intracellular miRNA‐21. Thus, upon internalization into tumor cells, these mucin nanoparticles can deplete miRNA‐21 from the cytosol, which induces apoptosis in vitro and in vivo.
Ceren Kimna, Thomas Mayer, Di Zhang, Matthias Marczynski, Carolin A. Rickert, Fabio Henkel, Lennart J. K. Weiss, Friedrich C. Simmel, Yuxia Luan, Oliver Lieleg   +9 more
wiley   +1 more source

Australian strains of the avian coronavirus infectious bronchitis virus predominantly target the respiratory tract rather than the kidneys in specific-pathogen-free chickens. [PDF]

J Gen Virol
Quinteros JA, Loukopoulos P, Noormohammadi AH, Browning GF, Coppo MJC, Vaz PK, Legione AR, Fahri O, Thilakarathne DS, Onasanya AE, Gopakumar G, Armat M, Diaz-Méndez A.   +12 more
europepmc   +1 more source