Results 121 to 130 of about 2,575,445 (348)
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Memoria Americana, 2010 El rol de las casas en las sociedades aymaras coloniales ha sido un interrogante central al estudiar los sistemas de liderazgo y sucesión y el reparto de la autoridad de acuerdo a los patrones duales de ejercicio del poder.
María Carolina Jurado
doaj
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Connecting Neighbors: The Role of Settlement Houses in Building Social Bonds With Communities [PDF]
, 2001 Provides lessons learned from the model of service delivery provided by community settlement houses. Examines how the atmosphere, programs, and activities at settlement houses create, foster, and support relationships among ...
Kitty Barnes, Prudence Brown
core
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Analysis of Consumers' Perceptions of Buying Conditions for Houses [PDF]
This paper examines the determinants of consumers' buying attitudes for houses. Data on buying attitudes are from responses to the Surveys of Consumer Attitudes conducted by the Survey Research Center, University of Michigan.
Pami Dua
core
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Evolving Functional and Spatial Preferences in Saudi Housing Before, During, and After COVID-19
BuildingsThe COVID-19 pandemic reshaped the function of the home, shifting it from a private residence to a multifunctional hub for work, education, and daily life.
Maryam AlKhateeb
doaj +1 more source
Design of Family Space in the Reform-era Chinese Cities [PDF]
, 2013 This study investigates how architectural and interior design practice for residential properties in China changed significantly as the result of the policy of increasing private ownership in the 1980s. Before the reform policies (which commenced in 1978)
Gao, Yun
core