Results 91 to 100 of about 2,389,024 (311)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Greater Boston Housing Report Card 2010 [PDF]

, 2010
Analyzes 2010 survey results on Greater Boston's housing market conditions, including trends in production, rents, and home prices, with a focus on foreclosures, affordability, differential impact of the recession by type of housing, and student ...
Anna Gartsman, Barry Bluestone, Chase Billingham, Jessica Casey   +3 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Social Housing in the Irish Housing Market. ESRI WP594, June 2018 [PDF]

, 2018
This working paper traces the evolution of social supports for housing since 2004, including local authority (LA) housing, housing provided by Approved Housing Bodies (AHB) and support for renting in the private sector through schemes administered by the
Corrigan, Eoin, Watson, Dorothy
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Addressing housing needs in minimising the problems of post conflict housing reconstruction [PDF]

, 2013
Depleted human and social capital, displacement of people, destruction of property, weakened institutions and ruined economy are some of the legacies of conflicts.
Amaratunga, Dilanthi, Haigh, Richard, Seneviratne, K.   +2 more
core  

Cash-Cow into the Purse of Malaysian Property Investors: Students Housing Investment [PDF]

, 2017
Growing demand for higher education (HE) and increasing students enrolment in higher education institutions (HEI) has been a global issue especially in the last three decades and housing the growing student population has become a dilemma for all concern
Ghani, Zubairu Abubakar, Suleiman, Noralfishah   +1 more
core   +3 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Concrete Waste as a Cement Replacement Material in Concrete Blocks for Optimization of Thermal and Mechanical Properties

SHS Web of Conferences, 2014
The sustainability of the natural environment and eco-systems is of great importance. Waste generated from construction forces mankind to find new dumping grounds and at the same time, more natural resources are required for use as construction materials.
Rosman M.S., Abas N.F., Othuman Mydin M.A.   +2 more
doaj   +1 more source