Results 21 to 30 of about 775,271 (312)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook +6 more
wiley +1 more source
BuildingsThis study analyzes the shortcomings of South Korea’s current evaluation method of ventilation performance for apartment buildings and suggests improvements.
Soo Man Lee +3 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
English Housing Survey, 2018: Housing Stock Data: Special Licence Access
, 2021 copyright UK Data Service and data collection copyright owner.The English Housing Survey (EHS) is a continuous national survey commissioned by the Department for Communities and Local Government (DCLG) that collects information about people's housing ...
CADS Housing Surveys +1 more
core
“Running myself ragged”: stressors faced by peer workers in overdose response settings
Harm Reduction Journal, 2021 Background Peer workers or “peers” (workers with past or present drug use experience) are at the forefront of overdose response initiatives, and their role is essential in creating safe spaces for people who use drugs (PWUD). Working in overdose response
Zahra Mamdani +10 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Carbon stock status of urban green space in Suqian City and carbon sink potential of major tree species [PDF]
E3S Web of Conferences【Purpose】Urban green spaces mitigate carbon emissions, boost carbon sinks, and address environmental risks. Analyzing their types, carbon stocks, and key tree species' sequestration capacity aids in improving green space management.
Ge Zhiwei +6 more
doaj +1 more source
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
Un programa de tratamiento psicológico para personal exmilitar traumatizado en el Reino Unido
Avances en Psicología Latinoamericana, 2009 Una gran proporción de personas sin hogar en el Reino Unido corresponde a ex-miembros de las fuerzas armadas, quienes sufren además de enfermedades mentales.
John Gale +3 more
doaj