Results 71 to 80 of about 104,419 (239)

Nowhere to Go: A Crisis of Affordability in the Bronx [PDF]

open access: yes, 2013
The state of affordability in the Bronx has Nowhere to Go - the Bronx is in a full out crisis of affordability. New data reveals that more than half of all households in Bronx Community District 5 now pay more than 50% of their income on rent, something ...
Elizabeth Wisman, Gregory Lobo Jost
core  

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

open access: yesAdvanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija   +22 more
wiley   +1 more source

Compliant Polymeric Sheet‐Based Heat Exchangers

open access: yesAdvanced Science, EarlyView.
This work presents flexible, transparent, and deployable polymer heat exchangers that achieve a heat transfer capacity per cost up to 4x higher than the state of the art, surpassing both metal and other polymer counterparts. The tube‐on‐tube design enables efficient heat transfer without flow occlusion, while the lightweight, corrosion‐resistant, and ...
Richard J. Fontenot   +5 more
wiley   +1 more source

Mayoral views on housing production: do planning goals match reality? [PDF]

open access: yes, 2019
Mayoral Views on Housing Production: Do Planning Goals Match Reality? evaluates mayoral priorities relative to actual need. Based on our analysis, even the most ambitious mayors are not prioritizing sufficient development necessary to meet the demand for
Einstein, Katherine Levine   +1 more
core  

Design drivers for affordable and sustainable housing in developing countries [PDF]

open access: yes, 2017
Current demand for housing worldwide has reached unprecedented levels due to factors such as human population growth, natural disasters and conflict. This is felt no more so than in developing countries which have experienced disproportionate levels of ...
Bruen, J., Hadjri, Karim, von Meding, J.
core   +1 more source

Selective Targeting of Immune Checkpoints HLA‐G and CD47 Using Novel Dual Signaling Protein DSP216 Promotes Innate Anticancer Immunity

open access: yesAdvanced Science, EarlyView.
The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob   +12 more
wiley   +1 more source

Development of mortgage lending and issues of methodology for determining the housing affordability

open access: yesRussian Journal of Economics and Law, 2019
Objective: to study the development of mortgage lending in the Russian Federation from 2000 to 2017 and to assess its impact on the indicators of housing affordability for the population.Methods: analysis, synthesis, systemic approach, formal legal ...
A. L. Belousov
doaj   +1 more source

2011 State of Metropolitan Housing Report [PDF]

open access: yes, 2011
Examines issues of environmental justice and 2011 indicators of housing affordability in the Louisville area, including concentration of subsidized housing, segregation, poverty, homeownership, foreclosure, and homelessness.

core  

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

open access: yesAdvanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li   +25 more
wiley   +1 more source

Housing Affordability in the United States: Price-to-Income Ratio by Pareto Distribution

open access: yesGeographies
This study integrates the price-to-income ratio (PIR) with Pareto distribution characteristics to provide a novel approach for evaluating home affordability across U.S. counties. The methodology offers a new lens for the analysis of home affordability by
Francisco Vergara-Perucich
doaj   +1 more source

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