Results 31 to 40 of about 114,094 (217)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Towards sustainable development of social housing model in Serbia: Case study of Belgrade [PDF]

open access: yesSpatium, 2015
Social housing in Serbia has been experiencing drastic transformations over the last 25 years. Although new solutions have begun to develop, they are based predominantly on various types of local supported housing provisions, insufficient in ...
Đokić Vladan   +2 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Testing Housing Price Drivers in Santiago de Chile: A Hedonic Price Approach

open access: yesCritical Housing Analysis, 2023
Hedonic modelling is an empirical analysis technique that is widely used to review the housing market and unpack the main determinants of price.
Francisco Vergara-Perucich
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Influencing factors and spatial differentiation of rental housing in a smart city: A GWR model analysis

open access: yesMeasurement: Sensors
Smart cities leverage technology, data, and digital infrastructure to enhance residents' quality of life, fostering sustainability and operational efficiency. To this end, the price data of rental housing in Hefei in 2022 were hereby collected to build a
Wen Zhao, Jie Zhong, Jiale Lv
doaj   +1 more source

The study of housing ownership effect on the participation and decision independence of women in the urban (Case study: Sanandaj) [PDF]

open access: yesنشریه جغرافیا و برنامه‌ریزی, 2017
Housing is greatest asset of family, especially in third world countries. Since each economic source brings power of social and political, possess of housing and housing ownership brings also the many benefits.
SHahrivar Rostaei, Sonya Karami
doaj   +1 more source

Urban housing prices, female labor participation, and economic development in china: A theoretical and empirical analysis

open access: yesFrontiers in Psychology, 2023
China's housing distribution system has undergone a major transformation, and the country's housing markets have experienced a rapid price increase. However, the extent to which urban housing prices influence female labor participation (FLP) in labor ...
Yuan Li   +4 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

An interactive decision support method for real estate management in a multi-criteria framework – REMIND

open access: yesInternational Journal of Strategic Property Management, 2014
Managing a housing stock involves complex decision making such as the design of a multiyear action plan pertaining to the maintenance and upgrading of the properties.
Franck Taillandier   +4 more
doaj   +1 more source

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