Results 61 to 70 of about 114,886 (261)
Objectives and Barriers to Promoting Social Housing Policy in Urban Finland
According to Finnish national housing policy, social rental housing (ARA) plays a key role in providing affordable housing and combating segregation in growing urban regions, in particular in Finland’s three largest urban regions (Helsinki, Tampere and ...
Jarkko Rasinkangas +2 more
doaj +1 more source
Housing policy and the granting of mortgage loans in the city of Cúcuta
This reflection article focuses on housing policy and the granting of mortgage loans in the city of Cúcuta from promulgation of housing policy. It is a descriptive study of quantitative approach, non-experimental, transectional supported in document ...
Jhon Antuny Pabón-León
doaj +1 more source
Targeting WDR12 Unleashes T‐Cell‐Mediated Antitumor Activity in Melanoma by Destabilizing CD276
WDR12 cooperates with the chaperonin subunit CCT7 to maintain CD276 stability on tumor cells, suppressing T‐cell activity and promoting immune escape. SU14813, a small‐molecule WDR12 inhibitor, reduces CD276 stability and relieves CD276‐mediated T‐cell suppression.
Jie Pan +10 more
wiley +1 more source
Housing Concept and Analysis of Housing Classification
Housing is one of the most important life components giving shelter, safety and warmth, as well as providing a place to rest. There is a lack of unified definition for housing concept in Latvia.
Henilane Inita
doaj +1 more source
Brazilian National Housing Policy
Regarding the National Housing Policy in Brazil, this paper aims to identify how institutional capacities vary into municipalities, and if this variation is related to housing deficit rates.
Renata Mendes Bezerra
doaj +1 more source
This study reveals a novel GC therapy targeting cholesterol homeostasis. Inhibiting the SCAP sterol‐sensing domain causes lethal ER stress via cholesterol accumulation, paradoxically forcing continuous synthesis that triggers ferroptosis. The findings link sterol sensing, metabolic dysregulation, and ferroptosis, establishing an anti‐cancer paradigm ...
Qianqian Xu +17 more
wiley +1 more source
RHINO: An Integrative Multi‐Omics Framework Linking Circadian Physiology to Precision Medicine
RHINO (RHythmic Interacting Network for multi‐Omics) is an integrative framework that maps circadian regulation across diverse genetic and disease contexts and prioritizes druggable circadian targets. Released as an AI‐powered interactive web portal, RHINO unifies genetic, regulatory, disease, and drug–target information, enabling context‐specific ...
Ying Chen +12 more
wiley +1 more source
Population‐scale EDC–hormone association mapping among 4255 participants across demographic subgroups identifies phthalate metabolites as the most consistent signals associated with lower testosterone‐related markers in males. Integrative mechanistic validation prioritizes MCPP as a key phthalate metabolite linked to CYP17A1‐centered disruption of ...
Yanling Chen +14 more
wiley +1 more source
Housing Policy as Tool of Space Development of Regions
The article tries to develop an adaptive scenario for housing policy implementation in different types of Russian regions as a basis of the research the authors took the concept of grading factors that impact space development in accordance with current ...
M. I. Buzulutsky
doaj +1 more source
Autoantigen mRNA‐LNP Vaccination Drives Therapeutic Efficacy in Preclinical Models for Autoimmunity
Systemic and intramuscular delivery of autoantigen mRNA via lipid nanoparticles reprograms antigen‐presenting cells toward a mature, homeostatic state, driving antigen‐specific T cell exhaustion and providing therapeutic efficacy across autoimmune disease models.
Paulien Baeten +30 more
wiley +1 more source

