Results 211 to 220 of about 1,807,633 (298)

A Good Society (and how we make it). [PDF]

J Epidemiol Community Health
Pickett KE.
europepmc   +1 more source

Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer

Advanced Science, EarlyView.
Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang, Shilong Wang, Meng Wang, Ruixian Yu, Jingwu Yue, Lin Shao, Hui Zhang, Mengwen Zhu, Luyang Tian, Shuting Cheng, Weimin Qin, Yang Tang, Yi Han, Wenjia Wang, Liwei An, Yan Meng, Shi Jiao, Zhaocai Zhou   +17 more
wiley   +1 more source

What do we talk about when we talk about spatial determinants of health? A systematic review. [PDF]

Public Health Pract (Oxf)
Duric P, Rajcevic S, Djekic Malbasa J, Mulic D.   +3 more
europepmc   +1 more source

A 3D‐Printed SFE‐Graded Alloy Mitigates Cryogenic Discontinuous Plastic Flow and Hydrogen Embrittlement

Advanced Science, EarlyView.
A novel strategy features gradient composition and stacking fault energy‐tuned (CoCrMn)100‐2xFexNix fabricated via in situ alloying additive manufacturing. This design circumvents cryogenic discontinuous plastic flow and hydrogen embrittlement of metallic materials under quasi‐static loading and hydrogen‐rich environment relevant to lunar polar ...
Renhao Wu, Ao Geng, Peihao Geng, Hyojin Park, Eun Seong Kim, Sang‐Ho Oh, Stephan Schönecker, Xiaoqing Li, Tianlong Zhang, Shuhui Li, Byeong‐Joo Lee, Hyoung Seop Kim   +11 more
wiley   +1 more source

Mourning Mama: A Reflection on Care Deserved but Never Afforded. [PDF]

J Gen Intern Med
Herrera A.
europepmc   +1 more source

Synergistic Integration of Fe–N4 Single‐Atom Sites and Directionally Aligned Electrode Architecture for High‐Performance Lithium–Sulfur Batteries

Advanced Science, EarlyView.
A directionally ice‐templated sulfur cathode integrated with atomically dispersed Fe–N4 catalytic sites is developed for high‐performance lithium–sulfur batteries. The structure–catalysis synergy accelerates Li+ transport and polysulfide conversion, leading to high sulfur utilization and stable long‐term cycling performance.
Lin Shen, Yijia Zou, Yuming Wang, Erya Gao, Christopher S. Allen, Tianyi Zhang, Stephen J. Skinner, Nigel P. Brandon, Chun Huang   +8 more
wiley   +1 more source

From bottleneck to efficiency: Key areas for improving discharge management in healthcare - a qualitative study. [PDF]

Ger Med Sci
Vogel JN, Hilgenhof H, Honekamp I, Kleinschmidt C, Petereit A, Bühler V, Schmidt S.   +6 more
europepmc   +1 more source

Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications

Advanced Science, EarlyView.
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen, Jiahui Lai, Qiongjiao Zeng, Liangbin Zhou, Boguang Yang, Bin Zhang, Min Wang, Jiajing Zhou, Kieran Lau, Khoon S. Lim, Zhong Alan Li, Rocky S. Tuan   +11 more
wiley   +1 more source

Housing ableism in finding and maintaining housing among people with disabilities: A scoping review. [PDF]

PLoS One
Lindsay S, Öncil G, Leo S.
europepmc   +1 more source

Hederagenin Attenuates Morphine Addiction via GABAA1‐Mediated Modulation of Ca2+–CaMK–CREB Signaling in Ventral Tegmental Dopaminergic Neurons

Advanced Science, EarlyView.
Hederagenin is identified as a GABAA1‐targeting natural compound that suppresses morphine‐associated reward by restraining Ca2+–CaMK–cAMP–CREB signaling in ventral tegmental dopaminergic neurons. RVG29‐modified liposomal delivery further enhances brain accumulation and behavioral efficacy, providing a mechanistically defined strategy for natural ...
Hongyang Jiang, Ziting Zhou, Nannan Xue, Jiasi Deng, Yuanyuan Zhou, Xinying Lv, Yuxuan Wang, Yi Zhang, Haotian Pan, Geyan Xu, Yinkun Tao, Mengran Li, Xin Cui, Hongyue Ma, Qian Wang, Zhigang Lu   +15 more
wiley   +1 more source