Results 31 to 40 of about 20,378 (254)
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
High-Fidelity Optimization Framework for Helicopter Rotors [PDF]
, 2009 An optimization framework for helicopter rotors based on high-fidelity coupled CFD/CSM analyses is presented. For this purpose the optimization software DAKOTA has been linked to a parametric geometry unit, a mesh generation unit and a fluid-structure ...
Imiela, Manfred
core
Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin +8 more
wiley +1 more source
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source
Formation of H[over ¯]^{+} via radiative attachment of e^{+} to H[over ¯]
Physical Review Research, 2020 We consider the formation of positive ions of antihydrogen H[over ¯]^{+} via radiative attachment of incident positrons e^{+} to antihydrogen atoms H[over ¯].
A. Jacob +4 more
doaj +1 more source
Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias +3 more
wiley +1 more source
Verwendung von Hover Detection zur Verbesserung der Texteingabe auf Smartphones [PDF]
, 2017 Interaction with smartphones can be challenging for some users, especially with regards to text entry. In these handheld devices the available screen space limits the size of the user interfaces elements.
Pollmann, Frederic
core
Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park +5 more
wiley +1 more source
The Aerodynamic Performance of a Novel Overlapping Octocopter in Hover
AerospaceA novel octocopter with an overlapping rotor arrangement is proposed in this paper to increase the payload with a limited size. The aerodynamic performance was obtained by both experiments and numerical simulations with the rotor spacing ranging from 1.2
Yao Lei, Xiangzheng Zhao
doaj +1 more source