Results 81 to 90 of about 20,284 (287)
Advanced Materials Technologies, EarlyView.The hydroporator platform employs controlled hydrodynamic deformation for efficient mRNA and CRISPR/Cas9 delivery into primary human T cells, enabling allogeneic CAR‐T cell manufacturing. It preserves cell functionality and drives potent gene editing, CAR expression, and tumor cytotoxicity, while feature‐based analysis links these functional outcomes ...
Soohyun Jeon +6 more
wiley +1 more source
Advanced Optical Materials, EarlyView.All‐organic channel‐layer OFETs are shown to enable visible‐light photoprogramming via triplet‐sensitized diarylethene switching. Preferential localization of the photoswitch and organic sensitizer in intercrystalline amorphous domains preserves polymer crystalline packing while ensuring short‐range Dexter‐type triplet–triplet energy transfer and solid‐
Jieun Kwon +10 more
wiley +1 more source
A Soft Robotic Device for Targeted Massage Therapy of Residual Limbs
Advanced Robotics Research, EarlyView.Residual limb edema after amputation can hinder recovery and delay prosthetic fitting. This study presents a soft‐robotic wearable device that delivers sequential compression through pneumatic McKibben actuators. By replicating the principles of manual lymphatic drainage, the device generates controlled mechanotherapeutic pressure patterns, providing a
Maria Grazia Polizzotto +5 more
wiley +1 more source
Lignin Hydrogenolysis over Bimetallic Ni–Ru Nanoparticles Supported on SiO2@HPS [PDF]
, 2023 Аntonina А. Stepacheva +6 more
openalex +1 more source
Numerical Modeling of Photothermal Self‐Excited Composite Oscillators
Advanced Robotics Research, EarlyView.We present a numerical framework for simulating photothermal self‐excited oscillations. The driving mechanism is elucidated by highlighting the roles of inertia and overshoot, as well as the phase lag between the thermal moment and the oscillation angle, which together construct the feedback loop between the system state and the environmental stimulus.
Zixiao Liu +6 more
wiley +1 more source
Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1
Advanced Science, EarlyView.Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency +19 more
wiley +1 more source
Polibotánica, 2016 Soil fertility in the first 20 cm of six plots and a cloud forest (MCF) still preserved in Sta. María Chilchotla, north of Oaxaca, where the predominant MCF and grown landraces were evaluated.
Irma Reyes-Jaramillo
doaj
Advanced Science, EarlyView.A new class of biohybrid spheroids is engineered through the self‐assembly of adherent cells and extracellular matrix‐mimetic hydrogel microparticles (microgels). By mimicking a snowballing effect, this approach enables scalable formation of porous, millimeter‐scale spheroids with enhanced cell viability and molecular diffusion.
Zaman Ataie +7 more
wiley +1 more source
Advanced Science, EarlyView.CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He +17 more
wiley +1 more source
A Self‐Organized Liquid Reaction Container for Cellular Memory
Advanced Science, EarlyView.How cells restore epigenetic information lost during replication is not known. This work proposes a mechanism based on the formation of biomolecular condensates. These condensates are induced by the chromosome itself and serve as reaction vessels for reconstructing missing epigenetic markers.
Sukanta Mukherjee +4 more
wiley +1 more source